Results 301 to 310 of about 21,646,523 (374)

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

Easy-MODA: Simplifying standardised registration of scientific simulation workflows through MODA template guidelines powered by the Enalos Cloud Platform. [PDF]

Comput Struct Biotechnol J
Kolokathis PD, Sidiropoulos NK, Zouraris D, Varsou DD, Mintis DG, Tsoumanis A, Dondero F, Exner TE, Sarimveis H, Chaideftou E, Paparella M, Nikiforou F, Karakoltzidis A, Karakitsios S, Sarigiannis D, Friis J, Goldbeck G, Winkler DA, Peijnenburg W, Serra A, Greco D, Melagraki G, Lynch I, Afantitis A.   +23 more
europepmc   +1 more source

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao, Hongliang Ge, Chenchao Lin, Xiyue Wu, Jianwu Chen   +4 more
wiley   +1 more source

Innovative Bionics Product Life-Cycle Management Methodology Framework with Built-In Reverse Biomimetics: From Inception to Clinical Validation. [PDF]

Biomimetics (Basel)
Alemzadeh K.
europepmc   +1 more source

The mediating role of financial well-being in the relationship between housing affordability and mental health. [PDF]

Sci Rep
Jurčišinová V, Forbes CS, Ng JWJ, Želinský T.   +3 more
europepmc   +1 more source

A conceptual health state diagram for modelling the transmission of a (re)emerging infectious respiratory disease in a human population. [PDF]

BMC Infect Dis
Avramov M, Gabriele-Rivet V, Milwid RM, Ng V, Ogden NH, Hongoh V.   +5 more
europepmc   +1 more source

That men should put an enemy in their mouths to steal away their brains: Reconsidering the origins of model psychosis. [PDF]

Hist Human Sci
Perkins-McVey M.
europepmc   +1 more source

Pedagogical and conceptual models acting on nursing education planning: a bibliographic review

, 1999
Maria José Moraes Antunes, Luiza Y. Okudaira Shigueno, Paolo Meneghin   +2 more
openalex  

A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model.

Health Technol Assess
Westwood M, Armstrong N, Krijkamp E, Perry M, Noake C, Tsiachristas A, Corro-Ramos I.   +6 more
europepmc   +1 more source

Stretch and flow at the gliovascular interface: high-fidelity modelling of the mechanics of astrocyte endfeet

Causemann M, Enger R, Rognes ME.
europepmc   +1 more source