Results 51 to 60 of about 21,646,523 (374)

Temporal description logic for ontology-based data access [PDF]

open access: yes, 2013
Our aim is to investigate ontology-based data access over temporal data with validity time and ontologies capable of temporal conceptual modelling. To this end, we design a temporal description logic, TQL, that extends the standard ontology language ...
Artale, A.   +3 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Adopting qualitative data in conceptual system dynamic modelling

open access: yesConstruction Economics and Building, 2023
Qualitative data plays an important role in system dynamics (SD) modelling, particularly in model conceptualization. Among the various forms of data, information from the mental database of stakeholders is considered the most important which can be ...
Abba Mahmud   +4 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Conceptual quality modelling and integrated control of combined urban drainage system [PDF]

open access: yes, 2017
This paper presents the first results of conceptual quality modelling approach oriented to the integrated real-time control (RTC) strategy for urban drainage networks (UDN) and wastewater treatment plants (WWTP) developed in the European project LIFE ...
Cembrano Gennari, Gabriela   +8 more
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Conceptual modelling of organizations

open access: yesНаукові записки НаУКМА: Економічні науки, 2016
The article offers an approach to the modelling of organizations that uses three types of representation: behavioural, normative and conceptual. This approach allows to create meaningful organizational models that adequately represent the complexity of ...
Eduard Maltsev
doaj   +1 more source

Development of a conceptual model of childhood asthma to inform asthma prevention policies

open access: yesBMJ Open Respiratory Research, 2021
Background There is no definitive cure for asthma, as prevention remains a major goal. Decision analytic models are routinely used to evaluate the value-for-money proposition of interventions.
Mohsen Sadatsafavi   +8 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Croatian Cadastre Database Modelling

open access: yesKartografija i Geoinformacije, 2013
The Cadastral Data Model has been developed as a part of a larger programme to improve products and production environment of the Croatian Cadastral Service of the State Geodetic Administration (SGA).
Zvonko Biljecki   +5 more
doaj  

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