Results 221 to 230 of about 23,828,011 (387)

Conceptual models and cognitive learning styles in teaching recursion [PDF]

, 1998
Cheng-Chih Wu, Nell Dale, Lowell J. Bethel   +2 more
openalex   +3 more sources

Beta-blockade in the management of chronic heart failure: Another step in the conceptual evolution of a neurohormonal model of the disease [PDF]

, 1996
Milton Packer
openalex   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Evaluation of LSTM vs. conceptual models for hourly rainfall runoff simulations with varied training period lengths. [PDF]

Sci Rep
Fathi MM, Al Mehedi MA, Smith V, Fernandes AM, Hren MT, Terry DO.   +5 more
europepmc   +1 more source

High Arctic ecosystem states: Conceptual models of vegetation change to guide long-term monitoring and research. [PDF]

Ambio, 2020
Ravolainen V, Soininen EM, Jónsdóttir IS, Eischeid I, Forchhammer M, van der Wal R, Pedersen ÅØ.   +6 more
europepmc   +1 more source

A Conceptual Model for the Expansion of Behavioral Consultation Training

, 1992
Susan M. Sheridan, Diane Salmon, Thomas R. Kratochwill, Pamela J. Carrington Rotto   +3 more
openalex   +2 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Factors affecting healthcare workers burnout and their conceptual models: scoping review. [PDF]

BMC Psychol
Nagle E, Griskevica I, Rajevska O, Ivanovs A, Mihailova S, Skruzkalne I.   +5 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source