Results 111 to 120 of about 218,024 (323)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

A Bi-Polar Theory of Nominal and Clause Structure and Function [PDF]

open access: yes, 2004
It is taken as axiomatic that grammar encodes meaning. Two key dimensions of meaning that get grammatically encoded are referential meaning and relational meaning.
Ball, Dr. Jerry T.
core  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Conditions for interoperability [PDF]

open access: yes, 2005
Interoperability for information systems remains a challenge both at the semantic and organisational levels. The original three-level architecture for local databases needs to be replaced by a categorical four-level one based on concepts, constructions ...
Heather, Michael, Rossiter, Nick
core  

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Algorithms and implementation of functional dependency discovery in XML : a thesis presented in partial fulfilment of the requirements for the degree of Master of Information Sciences in Information Systems at Massey University [PDF]

open access: yes, 2006
1.1 Background Following the advent of the web, there has been a great demand for data interchange between applications using internet infrastructure.
Zhou, Zheng
core  

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Nuevas direcciones empíricas en la investigación e innovación de tecnología educativa para la evaluación del aprendizaje en línea: una aproximación conexionista [PDF]

open access: yes, 2015
RESUMEN De una muestra de 758 participantes se obtuvieron redes conceptuales sobre diferentes dominios del conocimiento. Modelamiento matemático y computacional permitió determinar comportamiento de un esquema mental en cada dominio.
González Trujillo, Claudia Jaquelina   +4 more
core  

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