Results 51 to 60 of about 218,024 (323)
NOSQL design for analytical workloads: Variability matters [PDF]
, 2016 Big Data has recently gained popularity and has strongly questioned relational databases as universal storage systems, especially in the presence of analytical workloads.
Abelló Gamazo, Alberto +2 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
On the Nature of the Conceptual Schemata Development of Architecture Students
Iconarp International Journal of Architecture and Planning, 2019 Embedded within the theoretical and conceptual frameworks implied by the schemata theory and studies on architectural precedent knowledge, the present study is based on a research that investigates and evaluates two major issues within the context of ...
Hakan Anay, Ülkü Özten
doaj +1 more source
The Other Side of Peirce's Phaneroscopy [PDF]
, 2019 Research on Peirce’s phaneroscopy has been done with and through the paradigm or the conceptual schema of “Being” — what has been critiqued by post-structuralist philosophers as the metaphysics of Being.
Ioannidis, Iraklis
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Journal of Neurodevelopmental Disorders, 2021 Background Conceptual knowledge frameworks termed schemas facilitate memory formation and are posited to support flexible behavior. In adults, the medial temporal lobe (MTL) and medial prefrontal cortex (mPFC) trade-off in supporting schema-based memory ...
Kevin M. Cook +8 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A layered view model for XML with conceptual and logical extensions, and its applications [PDF]
, 2006 University of Technology, Sydney. Faculty of Information Technology.EXtensible Markup Language (XML) is becoming the dominant standard for storing, describing and interchanging data among various Enterprises Information Systems (EIS), web repositories ...
Rajagopalapillai, R
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cognitive Semantic Study of the Preposition ‘Min’ in the Quran
Journal of Islamic and Religious Studies, 2019 The preposition ‘min’ is semantically more complex than what the traditional lexicaAl-syntactic approaches held it to be adverb or adverbial of place and time.
Sardaraz Khan +2 more
doaj +1 more source