Results 81 to 90 of about 218,024 (323)

Expression-Meaning and Vagueness [PDF]

open access: yes, 2019
Brian Loar attempted to provide the Gricean program of intention-based semantics with an account of expression-meaning. But the theory he presented, like virtually every other foundational semantic or meta-semantical theory, was an idealization that ...
Schiffer, Stephen
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

An Overview of the Network of Meanings of the Prepositions “Ala” in the Quran With the Cognitive Approach [PDF]

open access: yesآموزه‌های قرآنی, 2019
The word “Ala” is one of the Arabic prepositions used in many cases in the Quran. This in the sense of its proto-scene encodes the concept of transcendence. But all the uses of this term in the Qur'an are not limited to this proto-scene meaning.
Maryam Tavakolnia, Valiollah Hasoumi
doaj  

How students blend conceptual and formal mathematical reasoning in solving physics problems

open access: yes, 2012
Current conceptions of expert problem solving depict physical/conceptual reasoning and formal mathematical reasoning as separate steps: a good problem solver first translates a physical Current conceptions of quantitative problem-solving expertise in ...
Elby, Andrew   +3 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Managing polyglot systems metadata with hypergraphs [PDF]

open access: yes, 2018
A single type of data store can hardly fulfill every end-user requirements in the NoSQL world. Therefore, polyglot systems use different types of NoSQL datastores in combination.
F. Saltor   +8 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Conceptual schemas as propositional idealized cognitive models : in search of a unified framework for the analysis of knowledge organization

open access: yesCuadernos de Investigación Filológica, 2013
This paper addresses the issue of the organization of (propositional) knowledge in the form of conceptual networks. We follow closely Ruiz de Mendoza’s (1996) proposal in this respect and we try to make it compatible with the still programmatic proposals
Francisco José Ruiz de Mendoza Ibáñez   +1 more
doaj   +1 more source

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