Results 141 to 150 of about 345,125 (260)

Coproducing a conceptual understanding of unmet palliative care needs: stakeholder workshops using modified nominal group technique. [PDF]

BMC Palliat Care
Bone AE, Diggle M, Johansson T, Finucane A, Sleeman KE, Davies JM, Higginson IJ, Fraser LK, Murtagh FEM.   +8 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Aspects of acceptance: building a shared conceptual understanding. [PDF]

Front Psychol
Mrazek MD, Dow BR, Richelle J, Pasch AM, Godderis N, Pamensky TA, Rutila BA, Mrazek AJ.   +7 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Conceptual understanding and cognitive patterns construction for physical education teaching based on deep learning algorithms. [PDF]

Sci Rep
Zhao L, Wu G, Shao W, Ma X.
europepmc   +1 more source

Enhancing our conceptual understanding of state and trait self-efficacy by correlational analysis of four self-efficacy scales in people with spinal cord injury. [PDF]

BMC Psychol, 2020
van Diemen T, Craig A, van Nes IJW, SELF-SCI Group, Stolwijk-Swuste JM, Geertzen JHB, Middleton J, Post MWM.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Enhanced conceptual understanding through formative assessment: results of a randomized controlled intervention study in physics classes. [PDF]

Educ Assess Eval Account
Lichtenberger A, Hofer SI, Stern E, Vaterlaus A.   +3 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Genetically transitional disease: conceptual understanding and applicability to rheumatic disease. [PDF]

Nat Rev Rheumatol
Niewold TB, Aksentijevich I, Gorevic PD, Gibson G, Yao Q.   +4 more
europepmc   +1 more source