Results 131 to 140 of about 2,163,668 (282)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Investigating the impacts of future oil prices on the achievement of 1.5°C climate goal. [PDF]

iScience
Chen H, Gong K, Wang R, Zhang C.
europepmc   +1 more source

Concession Bargaining

, 2018
Federica Alberti, Sven J. Fischer, W. Güth, Kei Tsutsui   +3 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Elderly age and male gender as risk factors for Non Diagnostic cytology at thyroid fine needle aspiration: results of a large cytological series. [PDF]

Endocrine
Croce L, Chytiris S, Teliti M, Chiardi I, Coperchini F, Businaro LL, Magri F, Dorji T, Rotondi M.   +8 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Citizen science substantiates jellyfish occurrence in the Mediterranean Sea. [PDF]

Sci Rep
Zampardi S, Licandro P, Milisenda G, Scannella D, Piraino S, Boero F.   +5 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Treating hypertension with single pill combinations: a simple strategy to save costs for the patients and payers. [PDF]

J Hypertens
Pikkemaat M, Atkins ER, Rodgers A, Schutte AE.   +3 more
europepmc   +1 more source

Concession agreements in Russia: economic retrospective

POWER AND ADMINISTRATION IN THE EAST OF RUSSIA, 2017
openaire   +1 more source