Results 51 to 60 of about 717,994 (285)

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Incentives in cruise terminal concession contracts [PDF]

open access: yesResearch in Transportation Business & Management, 2014
Concession contracts are widely used to structure the relationship between public managing bodies of ports and entities that are granted the right to operate a terminal at a given port. This study initiates research on incentives in cruise port/terminal concession contracts by combining managerial insights with a more economic approach using game ...
Wang, G., Notteboom, T., Pallis, A.
openaire   +3 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

A game-theoretic approach to developing a concession renegotiation framework for user-pays PPPs

open access: yes, 2020
In public–private partnership (PPP) contracting, a common practice for the hosting government is to fix the contractual clauses before signing a concession agreement with private investors.
Hongyu Jin   +3 more
semanticscholar   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee   +4 more
wiley   +1 more source

New legal framework of concessions in Croatia

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2014
At the end of 2012, Republic of Croatia put into force new Concessions Act, adjusted to the Proposal for a Directive of the European Parliament and of the Council on the award of concession contract from 2011. New Act is an important change on concession
Goran Vojković
doaj  

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

RESPONSIBILITY FOR NON-COMPLIANCE WITH CONCESSION CONTRACTS RELATED TO USAGE OF PUBLIC GOODS

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
This paper is concerned with the problems which occur in Croatian law related to the institution of responsibility for breach of contract on concession, which is one of the fundamental elements of the concession relation.
Silvija Petrić
doaj  

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

open access: yesAdvanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares   +3 more
wiley   +1 more source

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