Results 181 to 190 of about 37,492 (304)

Community biocultural mapping reveals historical occupation and enables defense of African rainforests. [PDF]

Ambio
Massaha IDBB, Koto SE, Walters GM, Mabo HA, Makala F, Azeon PN, Mabo J, Mandoumilele PN, Hendje JP, Djia DB, Betotobeya HB, Ndongoabendje M, Maïdji E, Maloumambomba S, Koumokoukou D, Kotomoukaye G, Mbengoy F, Bobouagno B, Bopounda G, Ngouba DD, Akouboua Y, Haya M, Bleck SM, Djabouemi G, Bobeloubouangoy AJ, Malingui V, Ikakaboua D, Louma DT, Mbouya P, Imbembi GR, Eboulou F, Ipengongoy P, Moulingui G, Mabika H, Walker J, Bayadi MM, Cheseaux S, Mbélé AE, Froese GZL.   +38 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

<i>Pleurothallis pembertonii</i> (Orchidaceae, Pleurothallidinae), a new species from northwestern Ecuador in the Tropical Andes Biodiversity Hotspot. [PDF]

PhytoKeys
Monteros MF, Holcomb K, Baquero LE, Wilson M.   +3 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Ethnic Accommodation and the Backlash From Dominant Groups. [PDF]

J Conflict Resolut
Juon A.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Borderline Intellectual Functioning in India: In the 'No Man's Land'. [PDF]

Ann Neurosci
Sharma A, Maharjan S, Dangi A, Sharma R.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Beyond Visibility: Social Media, Trust, and Responsibility in Oncology. [PDF]

J Immunother Precis Oncol
Hajjar J, Lewis MA.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source