Results 61 to 70 of about 834,266 (237)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

«Los alertadores de corrupción» Conclusiones

open access: yesIDP, 2019
On 19th December 2018, the Universitat Oberta de Catalunya held a seminar entitled “The Corruption Whistleblowers”, led by Dr. Agustí Cerrillo, the Professor of Administrative Law.
Òscar Capdeferro
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Conclusiones [PDF]

open access: yes, 2006
Resumen de las conclusiones a las que se ha llegado tras las Jornadas de la Sección de Ciencias Médicas de Eusko Ikaskuntza-Sociedad de Estudios Vascos, sobre el tema de la Discapacidad y Dependencia en nuestra ...
BEGIRISTAIN ARANZASTI, José María
core   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Escucharte #53-Conclusiones Del Evento Métodos De Estudio En La formación Gramatical y Auditiva

open access: yes, 2020
Se presentan las conclusiones de un evento enfocado en los métodos de estudio aplicados a la formación gramatical y auditiva, destacando las principales estrategias, aprendizajes y reflexiones surgidas.
Amezquita Gaitán, John Alexander
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conclusiones finales

open access: yesArquitecturas del Sur, 2005
En el desarrollo de la arquitectura moderna en el sur de Chile se distingue dos etapas: la primera, desde la década de 1930 hasta el terremoto de 1960 o de la primera modernidad, en que se introducen y desarrollan los modelos aportados por el movimiento ...
Gonzalo Cerda Brintrup   +5 more
doaj  

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