Results 91 to 100 of about 1,937,609 (381)

Response to Comment on `Undamped electrostatic plasma waves' [Phys. Plasmas 19, 092103 (2012)]

open access: yes, 2013
Numerical and experimental evidence is given for the occurrence of the plateau states and concomitant corner modes proposed in \cite{valentini12}. It is argued that these states provide a better description of reality for small amplitude off-dispersion ...
Afeyan B.   +7 more
core   +1 more source

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer [PDF]

open access: yes, 2015
Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC).
Ades, F   +16 more
core   +2 more sources

Acoustic Enhancement of Sleep Slow Oscillations and Concomitant Memory Improvement in Older Adults

open access: yesFrontiers in Human Neuroscience, 2017
Acoustic stimulation methods applied during sleep in young adults can increase slow wave activity (SWA) and improve sleep-dependent memory retention. It is unknown whether this approach enhances SWA and memory in older adults, who generally have reduced ...
Nelly A Papalambros   +6 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Concomitant Discovery of Systemic Lupus and Multiple Myeloma: Is It a Coincidence?

open access: yesDubai Medical Journal
Introduction: It has been suggested that patients with autoimmune diseases are more likely to develop other malignancies. However, the association between lupus and multiple myeloma (MM) is still not much described in the literature.
Sara Anibar   +4 more
doaj   +1 more source

An observational study of concomitant immunotherapies and denosumab in patients with advanced melanoma or lung cancer

open access: yesOncoimmunology, 2018
After a case report of profound clinical response in a melanoma patient following treatment with an immune checkpoint inhibitor (ICI) and RANK-ligand inhibitor denosumab, we identified similar patients from electronic health records (EHR) and described ...
A. Liede   +7 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evaluation of the criteria for renewal of LHRH agonists in patients with prostate cancer: results of the ANAREN Study

open access: yesDrugs in Context
Introduction: Injectable extended-release formulations of luteinizing hormone-releasing hormone agonists (LHRHa) have simplified the treatment of prostate cancer with a satisfactory level of androgen castration.
Jesús Calleja-Escudero   +10 more
doaj   +1 more source

The acceleration of metastases after tumor removal and the paradoxical phenomenon of concomitant tumor resistance [PDF]

open access: yes, 2018
Although surgical extirpation of tumors is usually clinically recommended, tumor removal may entail an undesired side effect: the risk of accelerating the growth of metastases.
Chiarella, Paula   +3 more
core   +1 more source

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