Results 181 to 190 of about 1,204,981 (346)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Safety of Rimegepant in Patients Using Preventive Migraine Medications: A Subgroup Analysis of a Long-Term, Open-Label Study Conducted in the United States

Journal of Pain Research
Gary Berman,1 Alexandra Thiry,2 Robert Croop3 1Clinical Research Institute, Minneapolis, MN, USA; 2Pfizer Inc., New York, NY, USA; 3Biohaven Pharmaceuticals, New Haven, CT, USACorrespondence: Gary Berman, Clinical Research Institute, 825 Nicollet Mall ...
Berman G, Thiry A, Croop R
doaj  

Concomitant Neck of Femur and Greater Trochanter Fracture in a Young Adult - A Case Report. [PDF]

J Orthop Case Rep
Kotangale P, Chaudhary S, Jogani A, Jaiswal N, Sakharkar N, Tarte A.   +5 more
europepmc   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Comparison of the healing rate with meniscal repair concomitant with anterior cruciate ligament reconstruction and isolated meniscal repair based on magnetic resonance imaging signal intensity. [PDF]

Asia Pac J Sports Med Arthrosc Rehabil Technol
Cho Y, Ahn JH.
europepmc   +1 more source

EFFECT OF STARCH CONCOMITANTLY PRESENT ON DIGESTIBILITY OF FAT

, 1968
Keiko Hata, HIROKO OZAKI, Fumie Nakamura, Yasumasa Majima   +3 more
openalex   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Secondary Carpal Tunnel Release After Surgical Fixation of the Distal Radius: A Case-Control Study. [PDF]

Hand (N Y)
den Hengst S, Eppink K, Ghaderi N, Tuaño KR, Eberlin KR, Bhashyam AR.   +5 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Concomitant Cervical Spine Disease Worsens PROMIS Outcomes in Patients Undergoing Arthroscopic Rotator Cuff Repair. [PDF]

Orthop J Sports Med
Shaikh HJF, Malin ML, Jeong A, Anderson DE, Nicandri GT, Giordano BD, Voloshin I, Maloney MD, Mannava S.   +8 more
europepmc   +1 more source