Results 181 to 190 of about 1,610,336 (282)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Concomitant Versus Tailored Therapy Based on Antibiotic Resistance Profiles for <i>Helicobacter pylori</i> Eradication: A Systematic Review and Meta-Analysis. [PDF]
Khalid A +10 more
europepmc +1 more source
Surgical treatment of severe aortic valve stenosis with concomitant Fabry disease
Athanasia Vlachou +3 more
openalex +1 more source
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Exploratory evidence of mitigated immune imprinting following concomitant COVID-19 and influenza vaccination. [PDF]
Choi MJ +13 more
europepmc +1 more source
Plasma concentration of voriconazole under concomitant use of nirmatrelvir/ritonavir in patients with COVID-19: a multicenter retrospective study [PDF]
Hao Shi +4 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Serotonin Syndrome after Concomitant Treatment with Linezolid and Meperidine [PDF]
P. K. Das +3 more
openalex +1 more source

