Results 191 to 200 of about 5,517,215 (329)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Infection-related and Hepatobiliary Death Outcome Reports Involving Avacopan in the Japanese Pharmacovigilance Database. [PDF]

In Vivo
Ide N, Sako KI, Maeda T.
europepmc   +1 more source

Concomitant testicular infection by Zika virus and Schistosoma mansoni [PDF]

Revista da Associação Médica Brasileira, 2017
Joob, Beuy, Wiwanitkit, Viroj
openaire   +3 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Epidemiology and Predictors of 90-Day Mortality in Patients with <i>Clostridioides difficile</i> Infection: A Retrospective Single-Center Study from Galati, Romania. [PDF]

Microorganisms
Nicolcescu P, Popa GV, Matei MN, Plesea-Condratovici A, Iancu AV, Arbune M.   +5 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Temocillin for the Treatment of Urinary Tract Infections: First Italian Data from a Multicentre Real-World Experience. [PDF]

Antibiotics (Basel)
Benvenuto N, Lanzafame M, Venturini S, Zerbato V, Perosa A, Mori G, Del Fabro G, Cai T, Zanusso C, Di Girolamo FG, Colla S, Gerussi V, Koumaki V, Busetti M, Di Bella S.   +14 more
europepmc   +1 more source

Oral Gentamicin Gut Decontamination for Prevention of KPC-Producing Klebsiella pneumoniae Infections: Relevance of Concomitant Systemic Antibiotic Therapy

Antimicrobial Agents and Chemotherapy, 2014
C. Tascini, F. Sbrana, S. Flammini, E. Tagliaferri, F. Arena, A. Leonildi, I. Ciullo, F. Amadori, A. di Paolo, A. Ripoli, R. Lewis, G. Rossolini, F. Menichetti   +12 more
semanticscholar   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Model-informed AUC-guided dosing for parenteral vancomycin in critically ill patients: impact on target attainment and renal safety - a pre-post intervention study. [PDF]

BMC Pharmacol Toxicol
Gundlach L, Kunkel M, Scherf-Clavel O, Surat G.   +3 more
europepmc   +1 more source