Results 141 to 150 of about 678,951 (271)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

A new CBCT evaluation for individual assessment of midpalatal suture maturation: a retrospective analysis. [PDF]

Front Oral Health
Boggio A, Fiorillo G, Razzani E, Manes Gravina B, Mandelli G, Vinci R, Castellana F, Gastaldi G.   +7 more
europepmc   +1 more source

Concordance Extremis

AMA Journal of Ethics, 2001
openaire   +2 more sources

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

Advanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji, Xu Liu, Shuai Zhao, Sihan Zhou, Yufan Yang, Ping Zhang, Yu Shi, Wei Qin, Guibing Zhu, Yongguan Zhu, Yanzheng Gao, Jiandong Jiang, Baozhan Wang   +12 more
wiley   +1 more source

Patient Voice and Treatment Nonadherence in Cancer Care: A Scoping Review of Sentiment Analysis. [PDF]

Nurs Rep
Wreyford L, Gururajan R, Zhou X, Higgins N.   +3 more
europepmc   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Evaluating AI-driven precision oncology for breast cancer in low- and middle-income countries: a review of machine learning performance, genomic data use, and clinical feasibility. [PDF]

Front Digit Health
Salazar-Garcés LF, Morales-Urrutia E, Cashabamba F, Proaño Alulema RX, Leiva Suero LE.   +4 more
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Liquid biopsy and tissue biopsy for the detection of EGFR mutations in patients with stage III non-small-cell lung cancer: an observational real-world study. [PDF]

ESMO Open
Malapelle U, Nasirova F, Wang A, Cooper M, Salomonsen R, Baser E, Raiber-Moreau EA, Chuang Y, Kim YJ.   +8 more
europepmc   +1 more source

ConCorD - ConCorD final synthesis report

ConCorD - ConCorD final synthesis ...
openaire   +1 more source