Results 31 to 40 of about 2,626 (263)
In this article, I present the development of the Hungarian-language Catholic education in Transylvania in the context of the diplomatic relations between the Romanian Kingdom and the Holy See.
Szabolcs András
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The Right to Have Places of Worship: The Cemevi Case in Turkey
This study discusses the obligation of the state to provide places of worship to religious communities in society, or to grant such existing places a specific status in law and thus entitle them to benefit from some public privileges.
Omur Aydin, Bulut Gurpinar
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Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
La revisión del concordato de 1953: la reunión entre Casaroli y López Rodó (noviembre de 1973)
El Concilio Vaticano II constituyó un impulso decisivo para la transformación de la relación Iglesia-Estado en España. El Concordato de 1953, que era el marco jurídico que regulaba la relación entre el catolicismo y el Régimen de Franco, hubo de ser ...
Pablo Martín de Santa Olalla Saludes
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Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Interaction between the Church and the State (Not ) to the Letter:
Soon after the restoration of Independence in 1990, The Act for the Restitution of the Status of the Catholic Church in Lithuania was adopted, which declared cooperation between the State and the Church on the basis of parity.
Paulius V. Subačius
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Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source

