Results 41 to 50 of about 1,598,801 (337)

Behaviour of reinforcement in drop tower beam tests [PDF]

open access: yesMATEC Web of Conferences, 2020
Drop tower tests help to gain understanding about the general behaviour of reinforced concrete members under impact loading and to analyse strains and strain rates occurring within their reinforcement.
Leicht Lena   +3 more
doaj   +1 more source

Experimental Study of Negative Skin Friction of Pile Group Foundations for Offshore Wind Turbines on Artificial Islands

open access: yesJournal of Marine Science and Engineering
Constructing offshore wind turbines on artificial islands is considered a viable option, but negative skin friction (NSF) is a significant adverse factor that cannot be ignored.
Yeyu Yan   +5 more
doaj   +1 more source

The beetle elytron plate: a lightweight, high-strength and buffering functional-structural bionic material

open access: yesScientific Reports, 2017
To investigate the characteristics of compression, buffering and energy dissipation in beetle elytron plates (BEPs), compression experiments were performed on BEPs and honeycomb plates (HPs) with the same wall thickness in different core structures and ...
Xiaoming Zhang   +5 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Numerical Study of Cone Penetration Tests in Lunar Regolith for Strength Index

open access: yesApplied Sciences
The cohesive properties of lunar regolith, combined with a low-gravity environment, result in it having a distinct mechanical behavior from sandy soil on Earth.
Xueliang Zhao   +4 more
doaj   +1 more source

Research on Experimental and Numerical Methods for Mechanical Properties of Lightweight Hollow Precast Utility Tunnels

open access: yesBuildings, 2022
In this paper, the mechanical properties of hollow precast utility tunnels are studied by experimental and numerical methods. Through full-scale experiments, the failure modes of ordinary and hollow utility tunnels are studied, and the failure stages of ...
Yutao Feng, Weibin Li, Nan Lu
doaj   +1 more source

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim   +4 more
wiley   +1 more source

Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller   +12 more
wiley   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

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