Results 41 to 50 of about 1,246,775 (307)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Analysis of the Vertical Dynamic Response of SDCM Piles in Coastal Areas

Journal of Marine Science and Engineering
The stiffened deep cement mixing (SDCM) pile, as a new type of rigid–flexible composite pile, significantly enhances the vertical bearing capacity of traditional precast piles, thus holding broad application prospects in the substructure construction of ...
Yeyu Yan, Hongbo Liu, Guoliang Dai, Yufan Xiang, Chenhu Xu   +4 more
doaj   +1 more source

The beetle elytron plate: a lightweight, high-strength and buffering functional-structural bionic material

Scientific Reports, 2017
To investigate the characteristics of compression, buffering and energy dissipation in beetle elytron plates (BEPs), compression experiments were performed on BEPs and honeycomb plates (HPs) with the same wall thickness in different core structures and ...
Xiaoming Zhang, Juan Xie, Jinxiang Chen, Yoji Okabe, Longcheng Pan, Mengye Xu   +5 more
doaj   +1 more source

Development of a glass microbubble-based lightweight strain hardening cementitious composite (LW-SHCC): Experiment and numerical simulation

Case Studies in Construction Materials, 2023
In this study, lightweight strain hardening cementitious composites (LW-SHCC) was developed through mix proportion design and experimental tests. The modified Andreasen and Andersen (A&A) model was applied for dry materials mixture proportioning and ...
Chang Wu, Mingwen Xu, Yanli Su, Xinru Wang, Chenhua Jin   +4 more
doaj   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

GFRP reinforced concrete : environmental and movement characteristics [PDF]

, 2004
For the last few decades, research has been conducted in order to come over the problem of corrosion in steel reinforced concrete. Consequently, methods such as cathodic protection, epoxy coatings, concrete additives, etc., have been tried ...
Al-Salem, Sultan
core   +5 more sources

NEW REINFORCING BAR OF RUP “BMZ” PRODUCTION

Литьë и металлургия, 2004
The technology of conversion of new kinds of hardware with profile of new type, which will allow to increase considerably the mechanical properties of concrete components and to enhance the steel economy, is considered in the article.
N. V. Andrianov, V. A. Matochkin, A. N. Bondarenko, V. A. Tishchenko, I. N. Tihonov, V. Z. Meshkov, V. S. Gumeniuk, G. N. Sudakov   +7 more
doaj  

Flexural Behavior of 3D‐Printed Porous Bouligand‐Structured Polymers: Influence of Pitch Angle and Porosity

Advanced Engineering Materials, EarlyView.
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil, Edward D. McCarthy, Parvez Alam   +2 more
wiley   +1 more source

Electrodeposition in Structural Lattices of Variable Architectures

Advanced Engineering Materials, EarlyView.
Electrodeposition enables geometry‐sensitive, autonomous void filling while simultaneously tuning chemical and mechanical properties. The development of approaches that can autonomously fill and heal material voids and yield composites with tailorable properties is increasingly relevant in engineering.
Yeong‐Man Kwon, Jingwen Zhang, Guido Musso, Alessandro F. Rotta Loria   +3 more
wiley   +1 more source