Results 31 to 40 of about 2,975,186 (252)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Bacterial crack repair to concrete [PDF]

open access: yes, 2015
This study has demonstrated the potential S. pasteurii and consequently MICP holds in improving the integrity of finish to concrete, without the use of chemical based sealants.
Richardson, Alan, Pasley, Jack
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Alkali-Activated Concrete Via Oven and Microwave Radiation Curing

open access: yes, 2021
This chapter presents a comprehensive review on alkali-activated concrete via oven and microwave radiation curing, where the influences of oven and microwave radiation curing on the alkali-activated concrete (AAC) were investigated with respect to their ...
Soriano, L.   +4 more
core   +1 more source

What does “Internet” mean to us as we age? A multi-task investigation on the conceptualization of the technological domain across generations

open access: yesComputers in Human Behavior Reports
Technological progress is increasing rapidly, and keeping up is particularly challenging for older adults. Thus, adapting technological innovations to human needs has become urgent. The first step toward this aim is to understand how people conceptualize
Ilenia Falcinelli   +12 more
doaj   +1 more source

The Particularity of Emotional Words: A Grounded Approach

open access: yesRivista Internazionale di Filosofia e Psicologia, 2017
This work focuses on emotional concepts. We define concepts as patterns of neural activation that re-enact a given external or internal experience, for example the interoceptive experience related to fear.
Claudia Mazzuca   +2 more
doaj   +1 more source

Varieties of abstract concepts and their grounding in perception or action

open access: yesOpen Psychology, 2020
For a very long time, theorizing in the cognitive sciences was dominated by the assumption that abstract concepts, which lack a perceivable referent, can only be handled by amodal or verbal linguistic representations.
Kiefer Markus, Harpaintner Marcel
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Composite concrete columns of 3DP concrete and self-compacting concrete subjected to normal force [PDF]

open access: yes
Conventional concrete columns are cast in forms made of steel or wood. The work of erecting and dismantling the formwork is time-consuming and laborious. Steel forms can be used several times but wood forms are usually only used once or a small number of
Silfwerbrand, Johan
core   +1 more source

Abstract concepts and expertise: the case of institutional concepts

open access: yesScientific Reports
Recent views recognize that abstract concepts encompass a variety of exemplars, each relying on different dimensions, including not only sensorimotor but also inner, linguistic, and social experiences.
Caterina Villani   +6 more
doaj   +1 more source

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