Results 111 to 120 of about 1,143,564 (302)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Corrosion assessment on reinforced concrete and its service life prediction [PDF]

, 2005
Deterioration of structural concrete may be caused either by chemical or physical effects. Corrosion of embedded steel is a major cause of deterioration of concrete structures at the present time.
Syed Mohamad, Syed Burhanuddin Hilmi
core  

Experimental Investigations on the Temperature Increase of Ultra-High Performance Concrete under Fatigue Loading

Applied Sciences, 2019
Leaner, more filigree, and resource-saving constructions are the development goal of the in the building industry. In reinforced concrete construction, a ultra-high strength concrete was developed to achieve these goals.
Melchior Deutscher, Ngoc Linh Tran, Silke Scheerer   +2 more
doaj   +1 more source

Generalized Mechanism Model for Ecosystem Hysteresis

Advanced Science, EarlyView.
A simplified model examines ecosystem transitions into alternative states after disturbances by leveraging positive and negative feedbacks. It identifies critical tipping points and quantifies hysteresis. Tests conducted on lakes, grasslands, and pitcher‐plant leaves align closely with empirical data and enable the prediction of recovery trajectories ...
Yanbin Hao, Xin Wang, Jie Liu, Mingzi Wu, Jianqing Du, Kai Xue, Xiaoning Song, Xiaoyong Cui, Tong Zhao, Yanfen Wang   +9 more
wiley   +1 more source

Analytical Formulation and Optimization of the Initial Morphology of Double-Layer Cable Truss Flexible Photovoltaic Supports

Buildings
With the rapid development of the photovoltaic industry, flexible photovoltaic supports are increasingly widely used. Parameters such as the deflection, span, and cross-sectional dimensions of cables are important factors affecting their mechanical and ...
Zenghui Di, Fei Wang, Hualong Yu, Xiang Dai, Bin Luo, Xin Liu   +5 more
doaj   +1 more source

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

Experimental Study of the Effectiveness of Strengthening Reinforced Concrete Slabs with Thermally Prestressed Reinforcement

CivilEng
Conventional strengthening measures for existing structures are usually not effective for the self-weight, which accounts for around 70% of the total load in reinforced concrete structures.
Yannik Schwarz, David Sanio, Peter Mark
doaj   +1 more source

Unanticipated Interfacial Redox Reaction in the NiOx Transport Layer of Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
This study presents the unanticipated interfacial redox reaction between NiOx and perovskite, which is characterized by XPS. This redox reaction is one of the primary reasons for the bias‐induced instability of PeLEDs and is particularly suppressed by simply applying an interface layer between NiOx and perovskite.
Thi‐Hoai Do, Aswaghosh Loganathan, Yun‐Han Wu, Yaw‐Shyan Fu, Tzung‐Fang Guo   +4 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source