Results 101 to 110 of about 331,242 (341)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Le patrimoine mondial est-il un mirage économique ?Les enjeux contrastés du développement touristique

open access: yesTéoros, 2011
La Liste du patrimoine mondial de l’UNESCO est réputée reposer sur des principes d’universalité. Cependant, ses contempteurs observent que la multiplication des sites inscrits, puis l’élargissement des catégories de patrimoine, s’accompagnent d’une ...
Lionel Prigent
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Les alternatives scolaires face à l’école publique : concurrence ou complémentarité ?

open access: bronze, 2022
Caroline Bertron   +5 more
openalex   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

Research Paper: Investigating the Role of the Dzyaloshinskii-Moriya Interaction and External Magnetic Field in Increasing Endurance against Thermal Fluctuations [PDF]

open access: yesفیزیک کاربردی ایران
In this paper, a two-spin system, under the Ising model and the Dzyaloshinskii-Moriya interaction, has been analyzed in different external magnetic fields.
Mohammad Reza Soltani, Maryam Mahmoudi
doaj   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting   +12 more
wiley   +1 more source

Les élites anciennes et nouvelles au Japon

open access: yesRevue Internationale d’Éducation de Sèvres, 2005
Japan, country of a thousand and one gods, almost always comes in the plural, with a multiplicity of elites and a myriad of divinities. However, since 1868, a new type of elite, imported from the “western” model, has developed: the meritocratic elite ...
Jean-François Sabouret
doaj   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta   +18 more
wiley   +1 more source

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