Results 261 to 270 of about 304,318 (354)

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba   +8 more
wiley   +1 more source

Risk Compensation After Initiation of Daily Oral Pre-exposure Prophylaxis Among Sexual and Gender Minorities in Nigeria. [PDF]

open access: yesArch Sex Behav
Adeyemi OA   +10 more
europepmc   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi   +7 more
wiley   +1 more source

Prevalence of syphilis among people living with HIV who attend a large urban antiretroviral therapy clinic in Panama: a cross-sectional epidemiological study. [PDF]

open access: yesTher Adv Infect Dis
Gabster A   +14 more
europepmc   +1 more source

Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche

open access: yesAdvanced Healthcare Materials, EarlyView.
Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson   +3 more
wiley   +1 more source

Isla: integrating full-scale ISA semantics and axiomatic concurrency models (extended version). [PDF]

open access: yesForm Methods Syst Des
Armstrong A   +4 more
europepmc   +1 more source

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