Results 51 to 60 of about 8,384 (311)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

A Deep Reinforcement Learning-Based Concurrency Control of Federated Digital Twin for Software-Defined Manufacturing Systems

Applied Sciences
Modern manufacturing demands real-time, scalable coordination that legacy manufacturing management systems cannot provide. Digital transformation encompasses the entire manufacturing infrastructure, which can be represented by digital twins for ...
Rubab Anwar, Jin-Woo Kwon, Won-Tae Kim
doaj   +1 more source

Survey on Optimization B+ Tree Index for Persistent Memory [PDF]

Jisuanji kexue
The advent of persistent memory(PM) introduces new perspectives for index structure design while presenting challenges in data consistency,persistence overhead,and concurrency control.As a widely adopted index structure in storage systems,the B+ tree ...
LU Chao, YANG Chaoshu, YAO Zhengzhu, LIU Ying, ZHANG Runyu
doaj   +1 more source

Extension and Implementation of Real-time Control Software Statecharts Model in Mechatronic System [PDF]

Jisuanji gongcheng, 2016
The control tasks without sequential properties in the control software of mechatronic system can not be clearly presented by monogamous statecharts model.According to the characteristics of tasks in real-time multi-task control system,tasks without ...
MA Yinyuan,WANG Hujun,ZHANG Wei
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

The impact of recovery on concurrency control

Proceedings of the eighth ACM SIGACT-SIGMOD-SIGART symposium on Principles of database systems, 1989
The paper investigates the constraints that recovery methods for transaction systems impose on concurrency control, a subject which seems to have been neglected by theoreticians so far. More specifically, two popular recovery methods are considered: update in place (in which the effects of a transaction that is aborted at some point are ``undone'') and
openaire   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

AI Agent-Based Blockchain Transaction Sequencer for Intent-Aware Transaction Ordering

IEEE Access
The execution order of concurrently submitted transactions in blockchain systems, as well as in database management systems, has a significant impact on applications, since different execution orders may lead to entirely different results.
Kyuin Jhi, Gi Seok Park
doaj   +1 more source