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Concurrent chemoradiotherapy for head and neck cancer
Seminars in Oncology, 2004Concurrent chemoradiotherapy (CRT) has been shown to be superior to radiotherapy (RT) alone in several clinical therapeutic settings for head and neck cancer (HNC). In unresectable disease, CRT is superior to RT alone, and for resectable advanced disease, it may serve as a substitute for initial surgery, with planned salvage surgery as a backup. In the
Bruce, Brockstein, Everett E, Vokes
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Strahlentherapie und Onkologie, 2016
The benefit of adjuvant chemotherapy (AC) in locoregionally advanced nasopharyngeal carcinoma (NPC) is controversial. This study compared concurrent chemoradiotherapy plus AC (CCRT/AC) with CCRT.Pair-matched analysis based on eight clinicopathological features of 244 patients treated with platinum-based CCRT/AC or CCRT alone was performed.
Yi-Yuan, Dong +14 more
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The benefit of adjuvant chemotherapy (AC) in locoregionally advanced nasopharyngeal carcinoma (NPC) is controversial. This study compared concurrent chemoradiotherapy plus AC (CCRT/AC) with CCRT.Pair-matched analysis based on eight clinicopathological features of 244 patients treated with platinum-based CCRT/AC or CCRT alone was performed.
Yi-Yuan, Dong +14 more
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Concurrent chemoradiotherapy for T2N0 glottic cancer
Toukeibu Gan, 2008T2N0声門癌に対する治療戦略は，T1声門癌と異なり多岐にわたる。本邦では，通常分割法による放射線単独治療が行われることが多いが，局所制御率は60～70%台と満足できる結果ではない（1～5）。根治性を高めるため，手術も行われるが，喉頭全摘出術は，根治性は高いものの，侵襲性の大きさから第一選択とはなり得ない。近年，術式の進歩とともに，喉頭亜全摘術（supracricoid laryngectomy with cricohyoidoepiglotto-pexy：CHEP）や喉頭部分切除術なども積極的に試みられるようになり，術後の発声機能の温存が図られるようになってきた。しかし，これらの術式でも，放射線治療による根治症例と比べると，発声機能は少なからず劣るため ...
Yuzuru Niibe +4 more
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Radiotherapy and Oncology
The effectiveness and safety of induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) in elderly patients with locoregionally advanced nasopharyngeal carcinomas (LANPCs) remain subjects of debate. This study evaluated the efficacy of IC+CCRT compared to CCRT alone in elderly LANPC patients.This retrospective, single-center study ...
Lin, Chen +5 more
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The effectiveness and safety of induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) in elderly patients with locoregionally advanced nasopharyngeal carcinomas (LANPCs) remain subjects of debate. This study evaluated the efficacy of IC+CCRT compared to CCRT alone in elderly LANPC patients.This retrospective, single-center study ...
Lin, Chen +5 more
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Concurrent chemoradiotherapy for primary cervical spinal cord germinoma
Journal of Clinical Neuroscience, 2009We report a rare case of primary intramedullary germinoma in the cervical spine of a 39-year-old woman without evidence of intracranial or disseminated disease. The germinoma was treated by a biopsy and follow-up concurrent chemoradiotherapy. This is the only reported case of primary spinal cord germinoma for which concurrent chemoradiotherapy was ...
Ka-Yen, Yang +5 more
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Concurrent chemoradiotherapy in head and neck cancer
Current Oncology Reports, 1999Historically, patients with unresectable head and neck cancer have been treated with definitive radiation therapy alone. In recent years, numerous trials have assessed the role of concurrent chemoradiation for these patients. Many of the larger, more recent trials are summarized here, with particular emphasis on the effect of combined therapy on ...
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Concurrent chemoradiotherapy for locoregionally advanced salivary gland malignancies
Head & Neck, 2011AbstractBackgroundLocoregionally advanced salivary gland malignancies have a poor prognosis despite aggressive therapy. Herein we report our experience in treating high‐risk salivary gland malignancies with concurrent chemoradiotherapy (CRT).MethodsMedical records of 15 patients with salivary gland malignancies treated with CRT at our institution ...
Lewis, Rosenberg +6 more
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Concurrent chemoradiotherapy in non-small cell lung cancer
Cochrane Database of Systematic Reviews, 2010This is an updated version of the original review published in Issue 4, 2004. The use of concurrent chemotherapy and radiotherapy in non-small cell lung cancer (NSCLC) might be seen as a way of increasing the effectiveness of radical radiotherapy at the same time as reducing the risks of metastatic disease.To determine the effectiveness of concurrent ...
Noelle, O'Rourke +3 more
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Concurrent Chemoradiotherapy for Esophageal Cancer With Malignant Fistula
International Journal of Radiation Oncology*Biology*Physics, 2008We reviewed clinical results of chemoradiotherapy (CRT) in the treatment of patients with advanced esophageal cancer with fistulae that developed before or during CRT.The study group included 16 patients with fistulous esophageal cancer treated by means of CRT between 1999 and 2006.
Ryuta, Koike +4 more
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Cancer Chemotherapy and Pharmacology, 2017
To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy vs. concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma (NPC).We reviewed data of locoregionally advanced NPC patients who underwent 2 different treatment plans, 1 with induction chemotherapy followed by concurrent ...
Jianyuan, Zhang +7 more
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To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy vs. concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma (NPC).We reviewed data of locoregionally advanced NPC patients who underwent 2 different treatment plans, 1 with induction chemotherapy followed by concurrent ...
Jianyuan, Zhang +7 more
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