Results 21 to 30 of about 549,379 (280)

Platinum prodrug nanoparticles inhibiting tumor recurrence and metastasis by concurrent chemoradiotherapy

open access: yesJournal of Nanobiotechnology, 2022
Background Although concurrent chemoradiotherapy (CRT), as one of the most effective antineoplastic therapies in clinic, can successfully inhibit the growth of tumor cells, a risk of developing secondary tumor is still an insurmountable barrier in ...
Wei-Zhou Jiang   +6 more
semanticscholar   +1 more source

Evaluation of Concurrent Chemoradiotherapy for Survival Outcomes in Patients With Synchronous Oligometastatic Esophageal Squamous Cell Carcinoma

open access: yesJAMA Network Open, 2022
Key Points Question Should concurrent chemoradiotherapy be considered for patients with synchronous oligometastatic esophageal squamous cell carcinoma (SOESCC), and which patients are suitable for early intensive treatment?
Zhenguo Shi   +16 more
semanticscholar   +1 more source

Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer: A Multicenter Randomized Phase 3 Clinical Trial.

open access: yesJAMA Oncology, 2021
Importance Most older patients with esophageal cancer cannot complete the standard concurrent chemoradiotherapy (CCRT). An effective and tolerable chemoradiotherapy regimen for older patients is needed.
Y. Ji   +58 more
semanticscholar   +1 more source

Interim result of phase II, prospective, single-arm trial of long-course chemoradiotherapy combined with concurrent tislelizumab in locally advanced rectal cancer

open access: yesFrontiers in Oncology, 2023
Background Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer, with modest benefits on tumor regression and survival.
Jiale Gao   +16 more
semanticscholar   +1 more source

Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis [PDF]

open access: yesClinical Endoscopy, 2019
Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here,
Hee Kyung Kim   +7 more
doaj   +1 more source

RATIONALE 311: tislelizumab plus concurrent chemoradiotherapy for localized esophageal squamous cell carcinoma.

open access: yesFuture Oncology, 2021
Definitive chemoradiotherapy is the standard of care for inoperable locoregionally advanced esophageal squamous cell carcinoma (ESCC). Immune checkpoint inhibitors such as anti-PD-1/PD-L1 antibodies have led to a paradigm shift in advanced, metastatic ...
R. Yu   +15 more
semanticscholar   +1 more source

TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer

open access: yesScientific Reports, 2021
Targeted sequencing for somatic mutations across the hotspots of 50 cancer-related genes was performed using biopsy specimens to investigate whether clinicopathological factors and genomic alterations correlated with prognosis in locally advanced ...
I. Kuno   +15 more
semanticscholar   +1 more source

Survival benefit of adding chemotherapy to intensity modulated radiation in patients with locoregionally advanced nasopharyngeal carcinoma. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:To evaluate the contribution of chemotherapy for patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated by intensity modulated radiotherapy (IMRT) and to identify the optimal combination treatment strategy.
Xuemei Ji   +5 more
doaj   +1 more source

EFFECT OF CONCURRENT CHEMORADIOTHERAPY ON PERIPHERAL BLOOD LYMPHOCYTES, CYTOKINES, AND GUT MICROBIOTA IN PATIENTS WITH PELVIC TUMOR [PDF]

open access: yes精准医学杂志, 2023
Objective To investigate the effect of concurrent chemoradiotherapy on immune function, inflammatory state, and gut microbiota in patients with pelvic tumor.
LYU Zhuochun, CHEN Xiaohui, QIN Chen, JU Fang
doaj   +1 more source

STAT3β Enhances Sensitivity to Concurrent Chemoradiotherapy by Inducing Cellular Necroptosis in Esophageal Squamous Cell Carcinoma

open access: yesCancers, 2021
Simple Summary The prognosis of esophageal squamous cell carcinoma (ESCC) patients is poor, with a five-year survival of 15–34%. We examined the expression of STAT3α and STAT3β in pretreatment tumor biopsies of 105 ESCC patients who received concurrent ...
Zhenyu Zheng   +13 more
semanticscholar   +1 more source

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