Results 81 to 90 of about 549,379 (280)
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
Induction chemotherapy with concurrent chemoradiotherapy versus concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of head and neck: a meta-analysis [PDF]
AbstractConcurrent chemoradiotherapy (CCRT) has been considered to be the standard of care for locally advanced squamous cell carcinoma of head and neck (LA-SCCHN). Whether induction chemotherapy (IC) with CCRT will further improve the clinical outcomes or not is still unclear.
Shipeng Li+5 more
openaire +2 more sources
Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen+3 more
wiley +1 more source
ABSTRACT Objectives To address controversies regarding target volume delineation for adjuvant intensity‐modulated radiation therapy for oral cavity squamous cell carcinoma with pedicled flap reconstruction and elective nodal irradiation (ENI). Materials and Methods During target volume delineation, the primary tumor bed was the pre‐surgical gross tumor
Sarbani Ghosh Laskar+20 more
wiley +1 more source
Subglottic small cell carcinoma (SSMCC) is a rare type of neoplasm, meaning that laryngeal cancer guidelines in several countries, including the National Comprehensive Cancer Network (NCCN) guidelines, do not include treatment principles for SSMCC ...
Man Chen+6 more
doaj +1 more source
At present, the standard treatment approach for locally advanced cervical cancer is concurrent chemoradiotherapy (CCRT). An elevated pretreatment squamous cell carcinoma antigen (SCC Ag) level is associated with extensive tumors and poor survival for ...
Jingxuan Fu+4 more
semanticscholar +1 more source
ABSTRACT Background Squamous cell carcinoma of the soft palate (SCCSP) represents a rare subtype of oropharyngeal cancer. This study aims to evaluate the treatment outcomes of SCCSP and to assess the prognostic significance of HPV status. Methods Patients diagnosed with SCCSP between January 1981 and December 2021 were collected. Survival outcomes were
Meng‐hua Li+11 more
wiley +1 more source
ABSTRACT Background This study aimed at identifying acoustic features of airway protective maneuvers as biomarkers of radiation‐associated dysphagia, involving penetration/aspiration and pharyngeal residue. Methods Temporal and spectral acoustical analyses were carried out on voluntary coughs, voluntary throat clearings, and reflexive coughs.
Sofiana Mootassim‐Billah+11 more
wiley +1 more source
Bone changes in patients undergoing pelvic radiotherapy remain unclear. This study initially utilized high-resolution peripheral quantitative computed tomography (HR-pQCT) to assess the dynamic changes in bone microarchitecture and volumetric bone ...
Weishi Cheng+9 more
doaj +1 more source
ABSTRACT Background Determining whether to treat the elective cervical lymph node (LN) area remains a dilemma in maxillary sinus squamous cell carcinoma (SCC). This study analyzed the patterns of initial LN involvement and recurrence to guide treatment strategies. Methods We retrospectively reviewed 119 patients with maxillary sinus SCC treated between
Jina Kim+4 more
wiley +1 more source