Results 51 to 60 of about 19,548 (258)

Study Concurrent Validity Antara script Consordance Test (SCT dan Multiple Choice Questions (MCQ) dalam Menilai Penalaran Klinik Mahasiswa Kedokteran

Jurnal Pendidikan Kedokteran Indonesia, 2016
Background: In the teaching process at medical faculty, there are many measuring devices have been used to evaluate the clinical reasoning ability. Each measuring device has the advantage and disadvantage. MCQ and SCT are the clinical reasoning measuring
Yeny Dyah Cahyaningrum, Gandes Retno Rahayu, Efrayim Suryadi   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Dynamic MRI to quantify musculoskeletal motion: A systematic review of concurrent validity and reliability, and perspectives for evaluation of musculoskeletal disorders.

PLoS ONE, 2017
PurposeTo report evidence for the concurrent validity and reliability of dynamic MRI techniques to evaluate in vivo joint and muscle mechanics, and to propose recommendations for their use in the assessment of normal and impaired musculoskeletal function.
Bhushan Borotikar, Mathieu Lempereur, Mathieu Lelievre, Valérie Burdin, Douraied Ben Salem, Sylvain Brochard   +5 more
doaj   +1 more source

PROMIS® General Life Satisfaction scale: construct validity in musculoskeletal pain patients

Chiropractic & Manual Therapies, 2020
Background Life satisfaction is part of subjective well-being. Measurement of life satisfaction is undertaken using self-report measures. This study aimed to evaluate the structural validity, concurrent validity, and internal structure of the PROMIS ...
Brett Vaughan, Jane Mulcahy, Kylie Fitzgerald   +2 more
doaj   +1 more source

Concurrent validity (Spearman correlation coefficient) of FACIT-TS-PS.

, 2023
Concurrent validity (Spearman correlation coefficient) of FACIT-TS-PS.
Ana Jovanovic (6787877), Masa Petrovic (17396580), Igor Krdzic (12042393), Tanja Jesic-Petrovic (17396583), Bojana Salovic (17396589), Ilic-Zivojinovic Jelena (17396592), Danka Vukasinovic (12042396), Ivan Soldatovic (3286998), Ana Tomic (17107509), Ivana Radovic (17396577), Aleksandar Matejic (17396586)   +10 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tests employed in the psychometric validation of the Insulin Treatment Appraisal Scale (ITAS) in T2DM patients; a systematic review of the literature

Journal of Patient-Reported Outcomes
Background Psychological Insulin Resistance (PIR) and negative perceptions regarding insulin treatment are noteworthy challenges in T2DM management, which hinder the timely initiation of insulin treatment.
Saba Rasheed, Anees ur Rehman, Zermina Tasleem, Marryam Azeem, Muhammad Fawad Rasool, Arifa Mehreen, Saleh Karamah Al-Tamimi   +6 more
doaj   +1 more source

The occupational sitting and physical activity questionnaire (OSPAQ): a validation study with accelerometer-assessed measures

BMC Public Health, 2020
Background The Occupational Sitting and Physical Activity Questionnaire (OSPAQ) was developed as an easy-to-use instrument for self-reported assessment of percentage sitting, standing, walking, and performing heavy labour in a workplace setting.
Iris Maes, Margo Ketels, Delfien Van Dyck, Els Clays   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source