Results 81 to 90 of about 422,589 (287)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Selective and eco-friendly procedures for the synthesis of benzimidazole derivatives. The role of the Er(OTf)3 catalyst in the reaction selectivity

open access: yesBeilstein Journal of Organic Chemistry, 2016
An improved and greener protocol for the synthesis of benzimidazole derivatives, starting from o-phenylenediamine, with different aldehydes is reported. Double-condensation products were selectively obtained when Er(OTf)3 was used as the catalyst in the ...
Natividad Herrera Cano   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Beyond Yield Optimization: The Impact of Organosolv Process Parameters on Lignin Structure

open access: yesMacromolecular Materials and Engineering, 2023
When optimizing the process parameters of the acidic ethanolic organosolv process, the aim is usually to maximize the delignification and/or lignin purity.
Jonas Bergrath   +5 more
doaj   +1 more source

To condense, or not to condense, that is the question

open access: yesJournal of Physics: Conference Series, 2014
Recent key experimental results on the spectroscopy of 12C have been made, which, when taken together, provide much needed clarity on the structure of the ground- and Hoyle- state excitations and provided new avenues for future research. High excitation energies in light nuclei are being explored with evermore precision and recent examples of this in ...
openaire   +1 more source

Charged condensation

open access: yesPhysics Letters B, 2008
1+11 pages; v2: comments and reference added, PLB ...
Gabadadze, Gregory, Rosen, Rachel A.
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Condensation heat transfer and pressure drop in flat tubes having different aspect ratio [PDF]

open access: yes, 2012
In this study, condensation heat transfer coefficients of R-410A were obtained in flattened stainless tubes made from 5.0 mm inner diameter round tubes.
Kim, Nae-Hyun   +2 more
core   +1 more source

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