Results 101 to 110 of about 79,106 (235)

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Classical criticality via quantum annealing. [PDF]

Nat Commun
Sathe P, King AD, Mniszewski SM, Coffrin C, Nisoli C, Caravelli F.   +5 more
europepmc   +1 more source

Membrane‐Mediated Force Transduction Drives Stick‐Slip Motion of Lipid Vesicles

Advanced Science, EarlyView.
A rotating magnetic field actuates a ferromagnetic particle inside a lipid vesicle, generating internal flows that induce stick‐slip propulsion near a surface. Membrane properties—elasticity, excess area, and phase behavior—modulate this motion by shaping stress dissipation and force transduction.
Paula Magrinya, Arin Escobar Ortiz, Juan L. Aragones, Laura R. Arriaga   +3 more
wiley   +1 more source

Gain engineering and atom lasing in a topological edge state in synthetic dimensions. [PDF]

Nat Commun
Tsuno T, Taie S, Takasu Y, Yamashita K, Ozawa T, Takahashi Y.   +5 more
europepmc   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

A giant of physics-in memory of Chen-Ning Yang. [PDF]

Natl Sci Rev
Zhang FC, Xue QK.
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Disentangling Brillouin's Negentropy Law of Information and Landauer's Law on Data Erasure. [PDF]

Entropy (Basel)
Lairez D.
europepmc   +1 more source

Giant Polar Displacements via Strain Relaxation in Itinerant Ferromagnet SrRuO3 Freestanding Films

Advanced Science, EarlyView.
The discovery of substantial Ru off‐centre displacements exceeding 30 pm in SrRuO3 freestanding films is reported, achieved by properly controlling the strain relaxation process to engineer an expanded lattice. The work shows that tailored strain relaxation strategies can be used to design magnetic polar metals with desired electronic states in ...
Xingcan Zhou, Zhangzhang Cui, Qiang Deng, Yechen Wang, Shuyu Dong, Zhou Wang, Qinwen Lu, Jianlin Wang, Qiuping Huang, Zhengping Fu, Bin Xiang, Qingyou Lu, Yalin Lu   +12 more
wiley   +1 more source