Results 121 to 130 of about 70,587 (187)

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

International Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi, Gilles S. van Tienderen, Shaojun Shi, Amy Broeders, Kathryn Monfils, Henk P. Roest, Luc J. W. van der Laan, Monique M. A. Verstegen   +7 more
wiley   +1 more source

Chirality and odd mechanics in active columnar phases. [PDF]

PNAS Nexus
Kole SJ, Alexander GP, Maitra A, Ramaswamy S.   +3 more
europepmc   +1 more source

Toward Informative Representations of Blood‐Based Infrared Spectra via Unsupervised Deep Learning

Journal of Biophotonics, EarlyView.
This study employs an unsupervised deep learning approach using a denoising autoencoder to distill blood‐based FTIR spectra into latent variables. By reducing noise and preserving essential information, the method enhanced lung cancer detection accuracy by 2.6%, providing a concise, clinically relevant representation of infrared spectra for improved ...
Corinna Wegner, Zita I. Zarandy, Nico Feiler, Lea Gigou, Timo Halenke, Niklas Leopold‐Kerschbaumer, Maik Krusche, Weronika Skibicka, Kosmas V. Kepesidis   +8 more
wiley   +1 more source

Characterizing G-type antiferromagnetism quantitatively with optical second harmonic generation. [PDF]

Light Sci Appl
Xu S, Ma C, Jin KJ, Zhang Q, Huang S, Wang Y, He X, Wang J, Xie D, Zhang Q, Guo EJ, Ge C, Wang C, Xu X, Gu L, He M, Yang G.   +16 more
europepmc   +1 more source

A New Approach for Calculating Texture Coefficients of Different Rocks With Image Segmentation and Image Processing Techniques

Microscopy Research and Technique, EarlyView.
This study calculated the texture coefficient (TC) values of 20 different rock textures with magmatic, metamorphic, and sedimentary origins, which underwent image segmentation using a novel approach. ABSTRACT The texture coefficient (TC) is a critical parameter used to analyze the microstructural characteristics of rocks and predict their mechanical ...
Emre Karakaya, Bilgehan Kekeç, Niyazi Bilim, Fatih V. Adigözel   +3 more
wiley   +1 more source

easyPARM: Automated, Versatile, and Reliable Force Field Parameters for Metal-Containing Molecules with Unique Labeling of Coordinating Atoms. [PDF]

J Chem Theory Comput
Abdelgawwad AMA, Francés-Monerris A.
europepmc   +1 more source

Pre‐treatment with extraction solvent yields higher recovery: Method optimization for efficient determination of polycyclic aromatic hydrocarbons in organic‐rich fine‐textured wastes

Journal of Environmental Quality, EarlyView.
Abstract Fluid fine tailings (FFT) contain numerous organic compounds, including polycyclic aromatic hydrocarbons (PAHs). Growing concerns of PAH toxicity warrants monitoring for environmental consequences and natural attenuation. Conventional Soxhlet extraction yields low (∼50%–60%) recovery of PAHs (naphthalene, phenanthrene, pyrene, dibenzofuran ...
Henian Guo, Najmeh Samadi, Maryam Firoozbakht, Alsu Kuznetsova, Tariq Siddique   +4 more
wiley   +1 more source

Condensed Matter Systems Exposed to Radiation: Multiscale Theory, Simulations, and Experiment. [PDF]

Chem Rev
Solov'yov AV, Verkhovtsev AV, Mason NJ, Amos RA, Bald I, Baldacchino G, Dromey B, Falk M, Fedor J, Gerhards L, Hausmann M, Hildenbrand G, Hrabovský M, Kadlec S, Kočišek J, Lépine F, Ming S, Nisbet A, Ricketts K, Sala L, Schlathölter T, Wheatley AEH, Solov'yov IA.   +22 more
europepmc   +1 more source

ATAC‐seq in Emerging Model Organisms: Challenges and Strategies

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan, Shadi Karimifard, Mozhgan Khodadadi, Liucong Ling, Luisa Linke, Ana Catalán, Vincent Doublet, Amanda Glaser‐Schmitt, Oliver Niehuis, Katja Nowick, Antonella Soro, Natascha Turetzek, Barbara Feldmeyer, Nico Posnien   +13 more
wiley   +1 more source

A multi‐proxy record of climate variability during the Loch Lomond Stadial (GS‐1) at Old Buckenham Mere, East England, UK

Journal of Quaternary Science, EarlyView.
ABSTRACT Northwest Europe experienced high‐amplitude climate change at the onset and end of the Younger Dryas (YD; ca 12 800–11 600 cal a BP), a crucial period to develop our understanding of natural climate dynamics. European palaeoclimatological records generally suggest a bipartite structure of the YD, potentially due to a northward retreat of the ...
Christopher P. Francis, Stefan Engels, Ian P. Matthews, Adrian P. Palmer, Katy Flowers, Ian Candy   +5 more
wiley   +1 more source