Results 121 to 130 of about 74,106 (203)

Out of the Crystalline Comfort Zone: Sampling the Initial Oxide Formation At Cu(111)

open access: yesAdvanced Science, EarlyView.
By combining replica exchange molecular dynamics with fast and efficient machine‐learned interatomic potentials, this computational study predicts the complex surface reconstructions accompanying the early Cu(111) surface oxidation. The unprecedentedly exhaustive sampling results in a high‐quality surface phase diagram that not only recovers known ...
Felix Riccius   +3 more
wiley   +1 more source

Compartmentalization and Aggregation of Biomolecular Condensates in Crowded Hydrogels for Enhanced Nucleic Acid Diagnosis

open access: yesAdvanced Science, EarlyView.
A cell‐mimetic hydrogel compartment is proposed to enhance the efficiency of enzymatic reactions. The naturally porous structure of a crowded hydrogel can simulate the intracellular microenvironment, promoting the aggregation of biomolecules and activity of DNA polymerase through excluded volume effects and compartmentalization.
Fangbin Xiao   +3 more
wiley   +1 more source

Mapping Charge Interactions in Intrinsically Disordered Proteins

open access: yesAdvanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips   +14 more
wiley   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

open access: yesAdvanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim   +4 more
wiley   +1 more source

Neutron Reflectometry on Superspreading and Non-Superspreading Trisiloxane Surfactants. [PDF]

open access: yesLangmuir
Reed J   +5 more
europepmc   +1 more source

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du   +5 more
wiley   +1 more source

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