Results 71 to 80 of about 6,287 (213)

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

Advanced Science, EarlyView.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo, Xiaojing Wang, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Jiaying Qu, Shunchen Zhou, Liduan Zheng, Qiangsong Tong   +9 more
wiley   +1 more source

One‐Step Tunable MoS2 with Enhanced Zn2+ Diffusion for High‐Energy Zinc‐Ion Hybrid Capacitors

Advanced Science, EarlyView.
A one‐step, scalable method introduces ethylene glycol into MoS2 layers, expanding the interlayer distance from 0.617 to 0.948 nm. This modification enhances the diffusion of hydrated Zn2+ ions, significantly improving charge‐discharge kinetics. Abstract Zinc‐ion hybrid capacitors (ZIHCs) offer a promising solution for large‐scale energy storage ...
Harshitha B. Tyagaraj, Vikram Mahamiya, Supriya J. Marje, Gagankumar Sakleshpur Kumar, Shalmali R. Burse, Swapnil R Patil, Ebrahim Al Hajri, Nilesh R. Chodankar, Yun Suk Huh, Young Kyu Han   +9 more
wiley   +1 more source

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

Advanced Science, EarlyView.
Aphids release salivary protein GLD into plants, which induces ROS in the phloem. This leads to the intermolecular disulfide bonds formation among SEO proteins, promoting their transition from the dispersed state to the aggregated state. SEO can interact with CMV CP.
Huijuan Guo, Qingyun Shi, Xiaoyu Ling, Yuting Wu, Lin He, Danyang Li, Keyan Zhu‐Salzman, Yucheng Sun   +7 more
wiley   +1 more source

Hyperelastic Starch Hydrogel Configures Edible and Biodegradable All‐Components for Soft Robots

Advanced Science, EarlyView.
Hyperelastic starch hydrogel is tailored via a phase separation strategy of solvent‐antisolvent co‐modulation. The mechanical performance of starch hydrogel is widely tuned with maximum strains: 194.4–361.4%; maximum tensile stresses: 34–192 kPa; and Young's moduli: 36.0–205.8 kPa. Notably, the hydrogel achieves complete soil degradation within 24 days
Siyu Yao, Haohao Hu, Mengfan Zhang, Qingqing Zhu, Donghong Liu, Shaoxing Qu, Guoyong Mao, Enbo Xu   +7 more
wiley   +1 more source

Cell Contractile Force‐Mediated Morphogenetic Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds

Advanced Science, EarlyView.
Through the actuation of cell contractile forces, geometrically complex structures are formed via a bioprinted, rapidly degrading cell‐laden hydrogel system, resulting in cell‐only condensation within a few days of culture. This system supports stem cell differentiation down different lineages and new tissue formation, such as chondrogenesis and ...
Aixiang Ding, Kaelyn L. Gasvoda, David S. Cleveland, Sriramya Ayyagari, Eben Alsberg   +4 more
wiley   +1 more source

Maximum Entropy Estimates of Hubble Constant from Planck Measurements. [PDF]

Entropy (Basel)
Knobles DP, Westling MF.
europepmc   +1 more source

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Genuine quantum scars in many-body spin systems. [PDF]

Nat Commun
Pizzi A, Kwan LH, Evrard B, Dag CB, Knolle J.   +4 more
europepmc   +1 more source

Smart Gated Hollow Mesoporous Silica Hydrogel for Targeting Endoplasmic Reticulum Stress and Promoting Periodontal Tissue Regeneration

Advanced Science, EarlyView.
The hollow mesoporous silica loaded with quercetin (HM‐QU@PEG) is combined with a thermosensitive anti‐bacterial matrix (TF127) to prepare HQUP@TF127. HQUP@TF127 effectively eliminates excessive ROS, alleviates endoplasmic reticulum stress, relieves mitochondrial calcium overload, and blocks the p53‐dependent apoptotic cascade. Furthermore, it enhances
Guichun Wang, Yuxiao Wang, Yang Ding, Xiang Chen, Shuhan Li, Wenqi Zhou, Rui Ma, Maomao Tang, Xinyuan Shao, Zixuan Shu, Ning He, Xiaodong Ma, Jian Guo, Chengjun Peng, Shuangying Gui   +14 more
wiley   +1 more source