Results 121 to 130 of about 492,283 (246)

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

Superior Electromechanical Power at Rare‐Earth Manipulated Glassy Morphotropic Phase Transitions

Advanced Science, EarlyView.
An effective physical approach named Rare‐earth Manipulated Glassy Morphotropic Phase Transitions has been experimentally developed and theoretically validated to achieve significant enhancements of 135% and 50% in electrostrain and elastic modulus of lead‐free ferroelectrics respectively, further enabling the significant boost of requisite driving ...
Le Zhang, Liqiang He, Shuyuan Xu, Haoyu Wang, Yunlong Sun, Yating Ran, Dong Wang, Kaiyun Chen, Junkai Deng, Zibin Chen, Danyang Wang, Michael A. Carpenter, Sen Yang   +12 more
wiley   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Inherited Nitrogen Distribution Control in Covalent Organic Framework Cathodes for Efficient Electrochemical Lithium Recovery via Capacitive Deionization

Advanced Science, EarlyView.
This study presents a rational design of hetero‐atom distribution within 2D‐COFs for selective electrochemical lithium extraction through capacitive deionization. The COF's high surface area and charge density facilitate effective lithium‐ion capture, offering a scalable and sustainable approach for lithium recovery from complex brine solutions ...
Rajesh Dhanushkotti, Abdul Khayum Mohammed, Kayaramkodath Chandran Ranjeesh, Hema Mylnahalli Krishnegowda, Najat Maher Aldaqqa, Dinesh Shetty   +5 more
wiley   +1 more source

Unassisted Switchable Dual‐Photoelectrode Devices Utilizing p‐n Carbon Quantum Dots as “Semiconductor Electrolytes”: Optimization Between H2O2 and Solar Electricity Production

Advanced Science, EarlyView.
p‐n type carbon quantum dots (N‐CQDs) are designed as a conceptually‐new “semiconductor electrolyte” to develop a self‐driven photoelectrochemical cell that can be switched to optimize between H2O2 production and electricity generation under visible‐light illumination with water and O2 as reaction reagents.
Hui‐Min Duan, Chen‐Guang Li, Liu‐Meng Mo, Jing‐Shuang Dang, Xiao‐Hui Jia, Jia‐Cheng Yu, Yu‐Hang Mei, Anders Thapper, Hong‐Yan Wang   +8 more
wiley   +1 more source

Amplified multipartite entanglement witnessed in a quantum critical metal. [PDF]

Nat Commun
Fang Y, Mahankali M, Wang Y, Chen L, Hu H, Paschen S, Si Q.   +6 more
europepmc   +1 more source

Sustainable High‐Performance Aqueous Batteries Enabled by Optimizing Electrolyte Composition

Advanced Science, EarlyView.
Lithium‐free aqueous batteries provide a safe, low‐cost alternative to lithium‐ion batteries for energy storage. This study introduces an optimized electrolyte using inexpensive salts, enhancing both energy density and cycling stability. The resulting battery delivers high power and efficiency, demonstrating strong potential for supercapacitor ...
Raphael L. Streng, Samuel Reiser, Anatoliy Senyshyn, Sabrina Wager, Johannes Sterzinger, Peter Schneider, David Gryc, Mian Zahid Hussain, Aliaksandr S. Bandarenka   +8 more
wiley   +1 more source

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Tunable vacuum-field control of fractional and integer quantum Hall phases. [PDF]

Nature
Enkner J, Graziotto L, Boriçi D, Appugliese F, Reichl C, Scalari G, Regnault N, Wegscheider W, Ciuti C, Faist J.   +9 more
europepmc   +1 more source