Results 61 to 70 of about 25,178,133 (232)
Maintenance optimization for rolling bearing based on delay time model
International Journal for Simulation and Multidisciplinary Design OptimizationRolling bearings are critical components in rotating machinery, directly influencing system reliability and performance. Bearing failures, driven by stochastic degradation processes, necessitate accurate reliability assessment and maintenance ...
Bui Minh-Hien +4 more
doaj +1 more source
Cost-Optimal Maintenance Planning for Defects on Wind Turbine Blades
Energies, 2019 Due to the considerable increase in clean energy demand, there is a significant trend of increased wind turbine sizes, resulting in much higher loads on the blades.
Yi Yang, John Dalsgaard Sørensen
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Maintenance data management for condition-based maintenance implementation
The ability to rapidly obtain significant and accurate information from extensive data records is a key factor for companies’ success in today's competitive environment.
Teixeira, Humberto +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rail Weld Defect Prediction and Related Condition-Based Maintenance
IEEE Access, 2020 Rail weld defects are major threats to railroad transportation. Enormous resources have been required for related maintenance. This paper presents a creative solution to predict weld defects and to classify railroads into different conditions based on ...
Nan Yao, Yuejun Jia, Kai Tao
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A Context-Aware Oil Debris-Based Health Indicator for Wind Turbine Gearbox Condition Monitoring
Energies, 2019 One of the greatest challenges of optimising the correct operation of wind turbines is detecting the health status of their core components, such as gearboxes in particular.
Kerman López de Calle +3 more
doaj +1 more source