Results 91 to 100 of about 26,419,102 (285)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Prediction cost maintenance model of office building based on condition-based maintenance [PDF]
Building maintenance costs are continuously increasing as a result of poor maintenance. Consequently, there is an urgent need to develop solutions to reduce the maintenance costs.
Au-Yong, C.P., Ahmad, F., Ali, A.S.
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modern techniques for condition monitoring of railway vehicle dynamics [PDF]
A modern railway system relies on sophisticated monitoring systems for maintenance and renewal activities. Some of the existing conditions monitoring techniques perform fault detection using advanced filtering, system identification and signal analysis ...
Gu, Fengshou +6 more
core +1 more source
EVALUATION PAVEMENT DISTRESSES USING PAVEMENT CONDITION INDEX [PDF]
Pavement deterioration is resulted by both environmental and structural causes. It is difficult to maintain the road on the same specification that was owned at the opening and problems start to appear represented in the pavement cracks, holes and ...
ZALTUOM, ALI MOHAMED ALI +2 more
core +1 more source
Corrosion Sensor Development for Condition-Based Maintenance of Aircraft
Aircraft routinely operate in atmospheric environments that, over time, will impact their structural integrity. Material protection and selection schemes notwithstanding, recurrent exposure to chlorides, pollution, temperature gradients, and moisture ...
Gino Rinaldi +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Due to the broad employment and large amount of electricity consumption of induction motor, their efficient operation has been a focus for engineering research.
Li YF(李延峰), Yu HB(于海斌)
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Condition-based maintenance (CBM) is becoming increasingly important because it performs more efficient diagnoses and prognoses based on equipment condition compared to time-based methods. CBM models greatly inform maintenance decisions.
Lo, Hanna
core

