Results 91 to 100 of about 26,419,102 (285)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Prediction cost maintenance model of office building based on condition-based maintenance [PDF]

open access: yes, 2014
Building maintenance costs are continuously increasing as a result of poor maintenance. Consequently, there is an urgent need to develop solutions to reduce the maintenance costs.
Au-Yong, C.P., Ahmad, F., Ali, A.S.
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modern techniques for condition monitoring of railway vehicle dynamics [PDF]

open access: yes, 2012
A modern railway system relies on sophisticated monitoring systems for maintenance and renewal activities. Some of the existing conditions monitoring techniques perform fault detection using advanced filtering, system identification and signal analysis ...
Gu, Fengshou   +6 more
core   +1 more source

EVALUATION PAVEMENT DISTRESSES USING PAVEMENT CONDITION INDEX [PDF]

open access: yes, 2011
Pavement deterioration is resulted by both environmental and structural causes. It is difficult to maintain the road on the same specification that was owned at the opening and problems start to appear represented in the pavement cracks, holes and ...
ZALTUOM, ALI MOHAMED ALI   +2 more
core   +1 more source

Corrosion Sensor Development for Condition-Based Maintenance of Aircraft

open access: yesInternational Journal of Aerospace Engineering, 2012
Aircraft routinely operate in atmospheric environments that, over time, will impact their structural integrity. Material protection and selection schemes notwithstanding, recurrent exposure to chlorides, pollution, temperature gradients, and moisture ...
Gino Rinaldi   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Three-phase induction motor operation trend prediction using support vector regression for condition-based maintenance

open access: yes, 2006
Due to the broad employment and large amount of electricity consumption of induction motor, their efficient operation has been a focus for engineering research.
Li YF(李延峰), Yu HB(于海斌)
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

ON THE APPLICATION AND COMPARISON OF CONDITION-BASED MAINTENANCE PROGNOSTICS APPROACHES: LOGICAL ANALYSIS OF DATA, ARTIFICIAL NEURAL NETWORKS, AND PROPORTIONAL HAZARDS MODELS

open access: yes, 2016
Condition-based maintenance (CBM) is becoming increasingly important because it performs more efficient diagnoses and prognoses based on equipment condition compared to time-based methods. CBM models greatly inform maintenance decisions.
Lo, Hanna
core  

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