Results 221 to 230 of about 26,419,107 (287)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Correction: Lago et al. Generation of Gellan Gum-Based Adipose-Like Microtissues. <i>Bioengineering</i> 2018, <i>5</i>, 52. [PDF]

Bioengineering (Basel)
Lago MEL, da Silva LP, Henriques C, Carvalho AF, Reis RL, Marques AP.   +5 more
europepmc   +1 more source

Nature-Positive for Industrial Facilities: An Environmental Management Framework for Biodiversity Stewardship. [PDF]

Environ Manage
Martín-Méndez Á, Campuzano-Bolarín F, López-López D.   +2 more
europepmc   +1 more source

Lightweight Machine Learning Framework for Cavitation Detection in Submersible Pumps Using Experimental Multi-Sensor Data. [PDF]

Sensors (Basel)
Celtek SA, Sattuf S, Shahnia F, Orhan N.
europepmc   +1 more source

Dynamic adjustment algorithm of equipment maintenance cycle based on substation state operation and maintenance. [PDF]

PLoS One
Yan Y, Zhou F, Cai Z, Lu H.
europepmc   +1 more source

Design of a digital health intervention to promote prediabetes health literacy and behavior change among young adults. [PDF]

Contemp Clin Trials Commun
Harrington CB, Webb K, Linder A, Wilson B, Linarte C, Campbell D, Hill K, Henry T, Dodson D, Doherty I.   +9 more
europepmc   +1 more source

Preventive Prosthodontics: Integrating Preventive Prosthodontic Principles Into the Indian Oral Health Policy Framework. [PDF]

Int J Dent
Anirudh BVM, Janette RS, Mahesh M.
europepmc   +1 more source