Results 221 to 230 of about 330,463 (281)

Enhancing Severe Neutropenia Prediction: PKPD‐Informed Labeling for Machine Learning Models Trained on Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
Accurately labeling outcomes in real‐world data for machine learning is challenging due to data sparsity and imbalances. This study developed and evaluated a pharmacokinetic–pharmacodynamic (PKPD)‐informed labeling strategy to enhance the risk prediction of docetaxel‐induced neutropenia.
Conor J O’Hanlon, Jonas Denck, Elif Ozkirimli, Stefanie Bendels, Candice Jamois, Clarisse Chavanne, Dirk Fey, Kimmo Porkka, Oscar Brück, Ken Wang   +9 more
wiley   +1 more source

Deep active optimization for complex systems. [PDF]

Nat Comput Sci
Wei Y, Peng B, Xie R, Chen Y, Qin Y, Wen P, Bauer S, Tung PY, Raabe D.   +8 more
europepmc   +1 more source

Navigating Sustainability Challenges Through Innovation: Dynamic Capabilities in the Italian Wineries

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT As environmental pressures and corporate social responsibility demands intensify, organizations face growing pressure to adopt adaptive, sustainability‐oriented strategies. This challenge is especially relevant in globally significant industries such as wine production, which is economically and culturally vital in countries like Italy.
Leonardo Agnusdei, Pier Paolo Miglietta, Giulio Paolo Agnusdei   +2 more
wiley   +1 more source

An efficient solution to Hidden Markov Models on trees with coupled branches. [PDF]

IEEE Trans Signal Process
Vafa F, Hormoz S.
europepmc   +1 more source

Self‐Serving CEO Activism? How the Business‐Relatedness of CEO Activism and CEO Morality Interact and Spill Over to CSR Motives

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Chief Executive Officer (CEO) activism, defined as chief executive officers publicly engaging with contentious sociopolitical issues, can evoke mixed stakeholder reactions and even harm a corporate reputation. Although the business‐relatedness of CEO activism has been highlighted as important, evidence of its impact on stakeholders remains ...
Kihyon Kim, Seon Min Lee
wiley   +1 more source

Optimal Transport based Cross-Domain Integration for Heterogeneous Data. [PDF]

J Am Stat Assoc
Yuan Y, Zhang Y, Shahbaba B, Fortin N, Cooper K, Nie Q, Qu A.   +6 more
europepmc   +1 more source

Does Institutional Ownership Structure Reduce Greenhouse Gas Emissions? An In‐Depth Study of Corporations Social Responsibility of European‐Listed Firms

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Motivated by the growing attention and concerns surrounding climate change and the potential role of institutional investors' ownership concentration (OC) in reducing corporations' greenhouse gas (GHG) emissions, this article explores the relationship between various forms of institutional ownership and firms' GHG emission intensity. To do so,
Daniele Giordino, Elisa Ballesio, Aradhana Galgotia, Laura Broccardo   +3 more
wiley   +1 more source

MG-DIFF: A novel molecular graph diffusion model for molecular generation and optimization. [PDF]

PLoS One
Zhang X, Wang S, Fang Y, Zhang Q.
europepmc   +1 more source

Corporate Environmental Responsibility, Environmental Policy Stringency and Debt Cost in Europe

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The financial implications of corporate environmental responsibility (CER) remain a subject of considerable debate, with empirical evidence often yielding mixed results. This ambiguity suggests that the relationship is contingent upon broader contextual factors, particularly the institutional environment.
Francisco José González Sánchez, Gracia Rubio Martín, Pedro López Sáez, Alejandro Rodríguez Martín   +3 more
wiley   +1 more source

Wild bootstrap for counting process-based statistics: a martingale theory-based approach. [PDF]

Lifetime Data Anal
Dietrich MT, Dobler D, de Gunst MCM.
europepmc   +1 more source