Results 31 to 40 of about 918 (167)

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Transparency, Sustainable Governance and Digital Accessibility in Municipalities: A Machine Learning Approach

open access: yesSustainable Development, EarlyView.
ABSTRACT Achieving the Sustainable Development Goals (SDGs) requires transparent and accountable local governments, yet little is known about the structural drivers of municipal transparency. This study introduces a machine learning approach to predict municipal transparency using the Bidimensional Transparency Index (BTI), which measures both the ...
Ana M. Plata‐Díaz   +3 more
wiley   +1 more source

A Technology‐First Framework for SDG Implementation in Carbon‐Based Economies: Empirical Evidence and Policy Implications

open access: yesSustainable Development, EarlyView.
ABSTRACT Only 17% of Sustainable Development Goal indicators are globally on track, yet the structural conditions explaining this failure remain inadequately theorised for fossil‐fuel‐dependent economies. This study develops and empirically tests a four‐layer loop framework of Technology, Well‐being, Social Equity, and Sustainability closing through ...
Sameh W. H. Al‐Muqdadi   +9 more
wiley   +1 more source

Is Reading an Upstream Predictor of Science and Mathematics Achievements in PISA? A Bayesian Network Analysis for Policy Educational Interventions on Socio‐Economic Dispersion and Gender Gaps

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This study investigates the structural relationships among reading, science and mathematics performance, socio‐economic dispersion (SES_Variance) and gender gaps using cross‐country PISA 2022 data. The primary objective is to assess whether reading functions as an upstream determinant of academic achievement and to evaluate the causal roles of
Simona‐Vasilica Oprea, Adela Bâra
wiley   +1 more source

Communicative Drills: The Impact of Communicative Intent on Oral Proficiency

open access: yesTESOL Quarterly, EarlyView.
Abstract This exploratory study investigated the role of communicative intent in second language (L2) oral practice by comparing communicative and meaningful drills. English language learners played a game designed to elicit repeated use of the second conditional.
Jonathan Serfaty
wiley   +1 more source

Participatory Research to Build Narrative Power: Results From Survey Research to Support Community Organizing for Health Justice and Equity

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points Community organizers addressing health issues use narrative strategy to shift public attitudes, build support for health‐affirming policies, and motivate collective action. Through a mixed methods research partnership with a power‐building organization, we evaluate how narrative power is leveraged to disrupt dominant ideas about the ...
YUSRA MURAD   +5 more
wiley   +1 more source

Informed Trade of Earnings Announcements

open access: yesJournal of Accounting Research, EarlyView.
ABSTRACT This paper examines how market participants trade on private information about firm fundamentals using the largest known case of informed trade of earnings announcements. From 2011 to 2015, a cartel of sophisticated traders illegally obtained early access to and traded on over 1,000 firm earnings announcements.
CHLOE XIE
wiley   +1 more source

Output Quality, Productivity, and Demand: Evidence from the Chinese Steel Industry

open access: yesThe RAND Journal of Economics, EarlyView.
ABSTRACT Unobserved objective output quality complicates the analysis of firm productivity and demand because higher‐quality products entail higher costs but offer greater consumption benefits. Using a panel of firms with output quality data, we decompose quantity‐based productivity into fundamental productivity and the costs of quality, and separate ...
Jing Li, Shengyu Li, Hongsong Zhang
wiley   +1 more source

Seek and Ye Might Not Find: The Effects of Contract Framing on Knowledge Sharing and Knowledge Seeking Qui cherche ne trouve pas toujours : les effets liés à la formulation des contrats sur le partage et la recherche de renseignements

open access: yesContemporary Accounting Research, EarlyView.
ABSTRACT We conduct two experiments to examine whether and how the framing (bonus vs. penalty) of a target‐based incentive contract affects knowledge sharing and knowledge seeking. In the first experiment, we predict and find that penalty‐framed contracts increase employees' stress due to the fear of potential loss, which in turn reduces their ...
Ta‐Tung (Stephanie) Cheng   +3 more
wiley   +1 more source

Auditor industry expertise and the predictive power of the deferred tax valuation allowance

open access: yesAccounting &Finance, Volume 65, Issue 1, Page 323-364, March 2025.
Abstract This paper investigates whether auditor industry expertise influences the predictive value of management earnings forecasts embedded in the deferred tax asset valuation allowance (VA). VAs depend on management's forecast of future taxable earnings and can provide investors with information about expected changes in future earnings.
Zhuoli Axelton   +2 more
wiley   +1 more source

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