Results 91 to 100 of about 622,309 (297)
MathematicsThis study derives explicit expressions for the Tail Conditional Expectation (TCE) and Tail Variance (TV) within the framework of the extended generalized skew-elliptical (EGSE) distribution.
Pin Wang +3 more
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Compositions of Conditional Risk Measures and Solvency Capital
Risks, 2016 In this paper, we consider compositions of conditional risk measures in order to obtain time-consistent dynamic risk measures and determine the solvency capital of a life insurer selling pension liabilities or a pension fund with a single cash-flow at ...
Pierre Devolder, Adrien Lebègue
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Conditional Expectation and the Efficiency of Estimates [PDF]
, 1951 Paul G. Hoel
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Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
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AN EVALUATION FORMULA FOR A GENERALIZED CONDITIONAL EXPECTATION WITH TRANSLATION THEOREMS OVER PATHS
, 2020 Dong Hyun Cho
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Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Advanced Science, EarlyView.Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
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KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression
Advanced Science, EarlyView.Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao +9 more
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Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
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The best possibility of the bound for the Kantrovich inequality and some remarks
Journal of Inequalities and Applications, 1997 The necessary and sufficient condition for equality to be attaind in the Kantrovich inequality is given and applied to an inequality of normal operators on Hilbert spaces.
Takahasi Sin-El, Tsukada M
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