Results 221 to 230 of about 35,767 (304)
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Identifying core adverse health outcomes for frailty assessment in older adults using administrative data. [PDF]
Silan M +3 more
europepmc +1 more source
On (anti) conditional independence in Dempster-Shafer theory
Mieczysław A. Kłopotek
openalex +1 more source
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin +10 more
wiley +1 more source
Causal Inference for First Non-Fatal Events With the Competing Risk of Death: A Principal Stratification Approach. [PDF]
Sun J, Cook T.
europepmc +1 more source
MARKOV BASES OF CONDITIONAL INDEPENDENCE MODELS FOR PERMUTATIONS
Villő Csiszár
openalex +1 more source
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu +12 more
wiley +1 more source
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang +3 more
wiley +1 more source
Bivariate Copula-Based Regression for Joint Modeling of Healthcare Visits. [PDF]
Marra G, Radice R.
europepmc +1 more source

