Results 191 to 200 of about 136,974 (263)

The Challenge of Handling Structured Missingness in Integrated Data Sources

Advanced Intelligent Discovery, EarlyView.
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson, Marius Hofert, Eleni‐Rosalina Andrinopoulou, Niels Hagenbuch, Sarah McGough, Chris Harbron, Robin Mitra   +6 more
wiley   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

Advanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee, Hyeonbin Moon, Junhyeong Lee, Seunghwa Ryu   +3 more
wiley   +1 more source

Real‐Time Multicolor Fluorescence Microscopy via Cross‐Channel Acquisition and Deep‐Learning‐Based Inference

Advanced Intelligent Discovery, EarlyView.
Sequential multicolor fluorescence imaging in dynamic microsystems is constrained by acquisition speed and excitation dose. This study introduces a real‐time framework to reconstruct spectrally separated channels from reduced cross‐channel acquisitions (frames containing mixed spectral contributions).
Juan J. Huaroto, Yuxin Jin, Nicholas Roy, Sarthak Misra   +3 more
wiley   +1 more source

Safety population size and duration of exposure prior to approval of new medicines: A database analysis of medicines centralised approved in the European Union between 2011 and 2023. [PDF]

PLoS One
Bouwman L, Leufkens H, Sepodes B, Torre C.   +3 more
europepmc   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

Advanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser, Haseeb Muhammad, Junaid Younas, Gillian Lovell, Bianca Migliori, Andreas Dengel, Sheraz Ahmed   +6 more
wiley   +1 more source

Combination treatment for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. [PDF]

J Clin Sleep Med
Buysse DJ, Arnedt JT, Buenaver L, Chang JL, Fernandez-Mendoza J, Patel SI, Zhou ES, Falck-Ytter Y, Hyer S, Kazmi U, Singh M, Wickwire EM.   +11 more
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

VAE+DDPG: An Attention‐Enhanced Variational Autoencoder for Deep Reinforcement Learning‐Based Autonomous Navigation in Low‐Light Environments

Advanced Intelligent Systems, EarlyView.
Variational Autoencoder+Deep Deterministic Policy Gradient addresses low‐light failures of infrared depth sensing for indoor robot navigation. Stage 1 pretrains an attention‐enhanced Variational Autoencoder (Convolutional Block Attention Module+Feature Pyramid Network) to map dark depth frames to a well‐lit reconstruction, yielding a 128‐D latent code ...
Uiseok Lee, Chanhong Hwang, Hyunseok Kang, Yechan Park, Hangwoo Jin, Tuan Anh Nguyen, Eunmi Choi, Dugki Min   +7 more
wiley   +1 more source

Data-driven prognostic factors analysis and personalized follow-up strategies for post-progression survival in locally advanced esophageal squamous cell carcinoma after definitive chemoradiotherapy. [PDF]

Ann Med
Qiu J, Wang Z, Ye Y, Yu Y, Chen M, Yang B.   +5 more
europepmc   +1 more source

Calibration‐Free Electromyography Motor Intent Decoding Using Large‐Scale Supervised Pretraining

Advanced Intelligent Systems, EarlyView.
Calibration‐free electromyography motor intent decoding is enabled through large‐scale supervised pretraining across heterogeneous datasets. A Spatially Aware Feature‐learning Transformer processes variable channel counts and electrode geometries, allowing transfer across users and recording setups. On a held‐out benchmark, fine‐tuned cross‐user models
Alexander E. Olsson, Nebojša Maleševic, Anders Björkman, Christian Antfolk   +3 more
wiley   +1 more source