Results 111 to 120 of about 2,017,563 (356)

Inferring Covariances for Probabilistic Programs [PDF]

open access: yesarXiv, 2016
We study weakest precondition reasoning about the (co)variance of outcomes and the variance of run-times of probabilistic programs with conditioning. For outcomes, we show that approximating (co)variances is computationally more difficult than approximating expected values.
arxiv  

Recent Estimates of Time-Variation in the Conditional Variance and in the Exchange Risk Premium [PDF]

open access: yes
The optimal-diversification model of investors' portfolio behavior can give a linear relationship between the exchange risk premium and the conditional exchange rate variance.
Jeffrey A. Frankel
core  

Altered Brain‐Behavior Association During Resting State is a Potential Psychosis Risk Marker

open access: yesAdvanced Science, EarlyView.
The study detects a potential multimodal biomarker that can be promising for identifying early markers of psychosis. It shows a consistent brain‐behavior association between a circuit of interconnected regions and executive function in neurotypical controls and individuals at various stages of psychosis.
Leonardo Fazio   +22 more
wiley   +1 more source

Which ergodic averages have finite asymptotic variance? [PDF]

open access: yesarXiv, 2016
We show that the class of $L^2$ functions for which ergodic averages of a reversible Markov chain have finite asymptotic variance is determined by the class of $L^2$ functions for which ergodic averages of its associated jump chain have finite asymptotic variance.
arxiv  

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Empirical Variance Minimization with Applications in Variance Reduction and Optimal Control [PDF]

open access: yesarXiv, 2017
We study the problem of empirical minimization for variance-type functionals over functional classes. Sharp non-asymptotic bounds for the excess variance are derived under mild conditions. In particular, it is shown that under some restrictions imposed on the functional class fast convergence rates can be achieved including the optimal non-parametric ...
arxiv  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Posterior Variance Analysis of Gaussian Processes with Application to Average Learning Curves [PDF]

open access: yesarXiv, 2019
The posterior variance of Gaussian processes is a valuable measure of the learning error which is exploited in various applications such as safe reinforcement learning and control design. However, suitable analysis of the posterior variance which captures its behavior for finite and infinite number of training data is missing.
arxiv  

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen   +12 more
wiley   +1 more source

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