Results 211 to 220 of about 2,017,563 (356)

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Unifying fragmented perspectives with additive deep learning for high-dimensional models from partial faceted datasets. [PDF]

NPJ Biol Phys Mech
Wu Y, Wu PH, Chambliss A, Wirtz D, Sun SX.   +4 more
europepmc   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Computer-based quantitative image texture analysis using multi-collinearity diagnosis in chest X-ray images. [PDF]

PLoS One
Quintero-Rincón A, Di-Pasquale R, Quintero-Rodríguez K, Batatia H.   +3 more
europepmc   +1 more source

Analysis of the conditional average and conditional variance of dissipated energy in the driven spin-boson model [PDF]

, 2017
Philip Wollfarth, Yasuhiro Utsumi, Alexander Shnirman   +2 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Reformulating the meta-analytical random effects model of the standardized mean difference as a mixture model. [PDF]

Behav Res Methods
Suero M, Botella J, Duran JI, Blazquez-Rincón D.   +3 more
europepmc   +1 more source

Observation of Optical Precursor in Time‐Energy‐Entangled W Triphotons

Advanced Science, EarlyView.
This study reports the observation of optical precursors at the triphoton level through the SSWM process. By appropriately adjusting the optical depth (OD), optical precursors are effectively separated from the main wave through utilizing the slow‐light effect to manipulate the triphoton temporal correlations in the group delay regime.
Zhou Feng, Rui Zhuang, Sinong Liu, Guobin Liu, Kangkang Li, Yanpeng Zhang   +5 more
wiley   +1 more source

Modified Kumaraswamy seasonal autoregressive moving average models with exogenous regressors for double-bounded hydro-environmental data. [PDF]

PLoS One
Armanini Stefanan A, Sagrillo M, Palm BG, Bayer FM.   +3 more
europepmc   +1 more source

The Molecular Basis of Amino Acids Sensing

Advanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang   +3 more
wiley   +1 more source