Results 161 to 170 of about 433,153 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Refrigerant and Oil Migration and Retention in Air Conditioning and Refrigeration Systems

open access: yes, 2005
Submitted by Megan Hayes (mohayes2@illinois.edu) on 2009-06-22T17:31:34Z No. of bitstreams: 1 TR240.pdf: 602129 bytes, checksum: d28e25a9154fb3902ab8cf9c1500f75a (MD5)Made available in DSpace on 2009-06-22T17:31:34Z (GMT). No. of bitstreams: 1 TR240.pdf:
Sheth, V.P., Newell, T.A.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Dynamic Modeling and Advanced Control of Air Conditioning and Refrigeration Systems

open access: yes, 2006
Over 15 billion dollars is spent on energy for residential air-conditioning alone each year, and air conditioning remains the largest source of peak electrical demand.
Rasmussen, Bryan P., Alleyne, Andrew G.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Design and Construction of a Mobile Air Conditioning Test Facility for Transient Studies

open access: yes, 1996
Compared to other air-conditioning and refrigeration systems, mobile air-conditioning systems are unique in the respect that they operate almost entirely under transient conditions.
Weston, P.G.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Ductless task air-conditioning

open access: yes, 2012
Task-ambient conditioning (TAC) systems have proven success in reducing power consumption, improving thermal comfort and enhancing air quality. However, the adoption of TAC has, however, been generally slow.
Jane Sargison (14748706)   +3 more
core  

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