Results 221 to 230 of about 1,540,087 (356)
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Investigate the bond performance of basalt FRP bars under the effect of severe conditions. [PDF]
Heshmat M, El-Shafie H, Elgabbas F.
europepmc +1 more source
The influence of age and condition of the tree upon seed production in western yellow pine /
Gareth A. Pearson
openalex +2 more sources
CXXII.—The molecular condition of mixed liquids. Part II. Application of Traube's atomic volume method to binary mixtures [PDF]
William Ringrose Gelston Atkins+1 more
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Gastrin-releasing peptide is essential for generalization of auditory conditioned fear under stress. [PDF]
Wu Y, Ni X, Mori H, Inoue R.
europepmc +1 more source
A report upon the condition of affairs in the territory of Alaska
Henry W. Elliott, Elliott Coues
openalex +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source