Results 221 to 230 of about 514,614 (257)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

No evidence for aversive associative olfactory memory through metamorphosis in Drosophila. [PDF]

Biol Open
Poppinga H, Mika R, Schwartz M, Schuldiner O, Meltzer H, Fiala A.   +5 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Comparative Effects of Training Modalities on Countermovement Jump Performance in Soccer Players: A Systematic Review and Network Meta-Analysis. [PDF]

J Sports Sci Med
Dong X, Li T, Xing W, Chen Z.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Correction: Xue et al. Untargeted Sweat Metabolomics and Targeted Plasma Amino Acid Profiling Reveal Dynamic Metabolic Remodeling During Conditioning in Yili Horses. <i>Biology</i> 2026, <i>15</i>, 1033. [PDF]

Biology (Basel)
Xue Y, Luo P, Shen Z, Meng C, Yao X, Meng J, Ren W, Wang T, Zeng Y.   +8 more
europepmc   +1 more source

Effects of a kennel conditioning protocol on transport-induced stress in minipigs: insights from heart rate variability and salivary cortisol. [PDF]

Vet Res Commun
Tognetti E, Paganelli A, Felici M, Sgorbini M, Lanatà A, Baragli P, Recchia FA, Gazzano A.   +7 more
europepmc   +1 more source

D-Flow SGLD: Source-Space Posterior Sampling for Scientific Inverse Problems with Flow Matching. [PDF]

J Comput Phys
Parikh MH, Chen Y, Wang JX.
europepmc   +1 more source

Tailored conditioning for hematopoietic stem cell transplantation in children with Mendelian susceptibility to mycobacterial disease: A tale of two pathways for IFN-γ and IL-12 defects. [PDF]

J Hum Immun
Ganesan K, Balwani M, Seshadri N, Muthukumar V, Krishnakumar K, Nalla Reddy A, Krishna V, Jayakumar I, Uppuluri R, Raj R.   +9 more
europepmc   +1 more source