Results 271 to 280 of about 1,581,275 (287)

Post-transplant cyclophosphamide in haploidentical stem cell transplantation: evaluating the impact of transplant conditioning intensity. [PDF]

Front Immunol
Pizzano U, Piemontese S, Facchin G, Greco R, Battista ML, Peccatori J, Fanin R, Ciceri F, Patriarca F, Lupo-Stanghellini MT.   +9 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Applying Bayesian Multilevel Modeling to Single Trial Dynamics: A Demonstration in Aversive Conditioning. [PDF]

Hum Brain Mapp
Farkas AH, Escobar JC, Gilbert FE, Panitz C, Ding M, Keil A.   +5 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Distinct bacterial communities affiliated with two types of shredder-produced particles in streams. [PDF]

FEMS Microbiol Ecol
Acharya P, Yegon MJ, Griebler C, Vitecek S, Attermeyer K.   +4 more
europepmc   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Biochemical markers and emerging therapies for intestinal manifestation of graft-versus-host disease. [PDF]

Front Immunol
Wiejak K, Przybyłkowski A, Tomaszewska A.   +2 more
europepmc   +1 more source

Clinical, immunological, molecular characteristics and outcomes of stem cell transplantation in <i>ZAP70</i> deficiency: a single-center experience. [PDF]

Front Immunol
AlQahtani F, Al Shaqaq A, Al-Saud B, AlRumayyan N, Mohammed R, Arnaout R, Elshorbagi S, Albuhairi S, Al-Ahmari A, Ayas M, Al-Saedi H, Hawwari A, Alazami AM, Al-Mousa H.   +13 more
europepmc   +1 more source