Results 281 to 290 of about 1,540,087 (356)
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Cell-type-specific synaptic scaling mechanisms differentially contribute to associative learning
Veneto F, Kepçe A, Wu YK, Gjorgjieva J.
europepmc +1 more source
Effects of breathing circuit insulation on inspired gas conditioning and water vapour condensation: an in vitro study. [PDF]
Nguyen-Minh T+3 more
europepmc +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
When Silence Breaks: The Influence of Pure Tones and White Noises on Conditioned Flight Responses. [PDF]
Matarazzo di Licosa SF+4 more
europepmc +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Soluble MHC class I chain-related protein A is a specific biomarker for the early detection of graft-versus-host disease. [PDF]
Kupis A+7 more
europepmc +1 more source