Results 201 to 210 of about 5,433,400 (294)

Obstetric haematology training: Optimising care through cultivated expertise. [PDF]

Obstet Med
Matusiak K, Pavord S, Shehata N.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Traces of Elements in the Electrochemical Reductive Amination of Acetone: Uncovering Bi as Substitute for Pb. [PDF]

Angew Chem Int Ed Engl
Kümper J, Guan Y, Kumari S, Mürtz SD, Sautet P, Palkovits R.   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

In situ muscle pre-activation shifts the lateral gastrocnemius muscle-tendon unit to rely on active fascicle lengthening to absorb peak power input. [PDF]

J Exp Biol
Vega D, Arellano CJ.
europepmc   +1 more source

Research on Constraint Conditions for Undesirable Deformationby Finite Element Analysis

Journal of the Japan Society for Technology of Plasticity, 2011
Takahiro MAKIYAMA, Toshiya TERAMAE, Keii UENO, Atsushi KANNO, Tetsuya YAGAMI, Yuki MURASATO   +5 more
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Characteristics and functionalities of digital tools supporting motivation and adherence to physical activity in older adults with health conditions: a protocol for a scoping review. [PDF]

BMJ Open
Burin-Chu S, Agbangla NF, Caby I, Bossede F.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Identification and characterization of salt-, drought-, and combined salt-drought stress-responsive <i>NHX</i> gene family in <i>Medicago sativa</i>. [PDF]

Plant Signal Behav
Kang B, Lu Y, Yang L, Khan S, Korai SK, Zulfiqar U, Alqahtani MD, Alasmari A, Gururani MA, Wang X.   +9 more
europepmc   +1 more source