Results 231 to 240 of about 5,397,821 (298)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Move to Improve: Co-Designing a Hospital-Based Physical Activity Program for Children With Chronic Health Conditions. [PDF]

Health Expect
Sivaramakrishnan H, Jones AF, Long T, Naylor L, Valentine J, Martin L, Haustead L, Shetty V, Wood F, Davis E, Move to Improve Author Group.   +10 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Thermo-hydro-mechanical response of energy-piled walls under varying wall configurations, pipe layouts, and seepage conditions. [PDF]

Sci Rep
Villegas L, Narsilio G, Fuentes R.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Presence of primordial Mg can explain the seismic low-velocity layer in the Earth's outermost outer core. [PDF]

Nat Commun
Liu T, Jing Z.
europepmc   +1 more source

Influence of elevation and shrub age on element accumulation in Vaccinium myrtillus in the alpine zone of the Low Tatras. [PDF]

Environ Monit Assess
Ballová ZK, Prodaj M, Solár J.
europepmc   +1 more source

Genome-wide identification and analysis of expression of pathogenesis-related protein 1 (PR-1) gene family in brown algae. [PDF]

Front Plant Sci
Teng L, Liang S, Chen J, Kobe B, Ye N, Wang H, Song J.   +6 more
europepmc   +1 more source

Consumer Engagement in Chronic Conditions Research: An Integrated Framework Informed by Recognition Theory. [PDF]

Health Expect
Zhou M, Parkinson A, Watts L, Veitch J, Suominen H, Desborough J.   +5 more
europepmc   +1 more source