An open-label, single-dose, randomized, parallel-group study of the safety and relative bioavailability of topical sildenafil cream vs oral sildenafil in healthy male adults. [PDF]
Cornell K +3 more
europepmc +1 more source
Purpose To examine systemic exposure and elution characteristics of liquid vancomycin‐soaked anterior cruciate ligament (ACL) grafts in vivo by assessing serum vancomycin levels over 48 hours after ACL reconstruction and comparing the resulting concentrations with the toxic threshold of 15 to 20 μg/mL.
Swen Witteveen +8 more
wiley +1 more source
Trends and factors associated with condom use among Tanzanian men before and after introduction of pre-exposure prophylaxis: evidence from TDHS 2010-2022 Tanzania Demographic and Health Surveys. [PDF]
Mwakilasa MT +3 more
europepmc +1 more source
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
List randomization for prevalence estimation of sensitive behavioral data among women with HIV of reproductive age in Lilongwe, Malawi. [PDF]
Diepstra K +7 more
europepmc +1 more source
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source
Measurement of Human Flourishing Constructs in Evaluation of Voluntary Family Planning Interventions: A Modified Scoping Review of the Literature. [PDF]
Suleiman AB, Cole C, Regalado S.
europepmc +1 more source
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Successful application of the condom technique in closure of a large coronary aneurysm-a case report. [PDF]
Knold J, Christensen MK, Jensen LO.
europepmc +1 more source
ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source

